Development of Membrane Protein Structural Biology in Australia

澳大利亚膜蛋白结构生物学的发展

• 批准号: nhmrc : 1004620
• 负责人: Dr Daniela Stock
• 金额: $ 40.11万
• 依托单位: Victor Chang Cardiac Research Institute
• 依托单位国家: 澳大利亚
• 项目类别: Research Fellowships
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/development-membrane-protein-biology-australia/109054
• 关键词: Development; Membrane; Protein; Structural; Biology

Membrane proteins are key components of all living organisms, constituting more than 30% of cellular proteins and representing more than 50% of all drug targets. Despite their medical importance our knowledge of membrane proteins is still extremely limited and requires further technological advances. This work will firmly establish membrane protein crystallography in Australia and provide a basis for training of new researchers in this important field.

膜蛋白是所有生物体的关键成分，占细胞蛋白的30%以上，占所有药物靶点的50%以上。尽管它们在医学上很重要，但我们对膜蛋白的了解仍然非常有限，需要进一步的技术进步。这项工作将奠定澳大利亚膜蛋白晶体学的基础，并为培养这一重要领域的新研究人员提供基础。