The structure and organization of the mitochondrial genome in health and mitochondrial disease
The structure and organization of the mitochondrial genome in health and mitochondrial disease
批准号:
nhmrc : 1041582
负责人:
A/Pr Aleksandra Filipovska
金额:
$36.92万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2013
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2013-01-01 至 2016-12-31
中文摘要
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英文摘要
Mitochondrial DNA (mtDNA) mutations and mitochondrial dysfunction have been associated with a wide range of multi-system human diseases, although much remains to be learnt about molecular mechanisms in the pathogenesis of these diseases. Our goal is to understand how the expression of the mitochondrial DNA is regulated by mtDNA-binding proteins that will allow us to provide important insights into the molecular mechanisms of mitochondrial diseases.
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会议论文
Targeting mitochondrial dysfunction in cardiovascular disease and cancer
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批准号:nhmrc : GNT1154646
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项目类别:Research Fellowships
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资助金额:$79.23万
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财政年份:2019
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负责人:A/Pr Aleksandra Filipovska
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依托单位:
Functional genomic analyses of mitochondrial disorders
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批准号:nhmrc : 1078273
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项目类别:Project Grants
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资助金额:$38.47万
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财政年份:2015
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负责人:A/Pr Aleksandra Filipovska
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依托单位:
Functional genomic analyses of mitochondrial disorders
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批准号:nhmrc : GNT1078273
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项目类别:Project Grants
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资助金额:$37.31万
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财政年份:2015
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负责人:A/Pr Aleksandra Filipovska
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依托单位:
Regulation of mitochondrial gene expression in disease
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批准号:nhmrc : GNT1058442
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项目类别:Research Fellowships
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资助金额:$66.45万
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财政年份:2014
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负责人:A/Pr Aleksandra Filipovska
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依托单位:
Regulation of mitochondrial gene expression in disease
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批准号:nhmrc : 1058442
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项目类别:Research Fellowships
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资助金额:$46.49万
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财政年份:2014
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负责人:A/Pr Aleksandra Filipovska
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依托单位:
Targeting the mitochondrial transcriptome to treat mitochondrial disease
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批准号:nhmrc : 1045677
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项目类别:Project Grants
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资助金额:$30.46万
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财政年份:2013
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负责人:A/Pr Aleksandra Filipovska
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依托单位:
Regulation of RNA processing in the mitochondrial disease MELAS
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批准号:nhmrc : 1023460
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项目类别:Project Grants
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资助金额:$34.74万
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财政年份:2012
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负责人:A/Pr Aleksandra Filipovska
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依托单位:
Mitochondrial ribosomal pentatricopeptide domain proteins regulate protein synthesis in health and disease
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批准号:nhmrc : 1005030
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项目类别:NHMRC Project Grants
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资助金额:$29.61万
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财政年份:2011
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负责人:A/Pr Aleksandra Filipovska
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依托单位:
The role of the cytoskeleton in communication between the L-type Ca2+ channel and the mitochondria in cardiac pathology
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批准号:nhmrc : 634501
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项目类别:NHMRC Project Grants
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资助金额:$36.2万
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财政年份:2010
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负责人:A/Pr Aleksandra Filipovska
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依托单位:
oxidatiive stress
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批准号:nhmrc : 513932
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项目类别:Early Career Fellowships
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资助金额:$0.5万
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财政年份:2009
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负责人:A/Pr Aleksandra Filipovska
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依托单位:
Regulation of gene expression in mitochondrial disease
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批准号:nhmrc : 572513
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项目类别:NHMRC Project Grants
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资助金额:$22.56万
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财政年份:2009
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负责人:A/Pr Aleksandra Filipovska
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依托单位:
Thiol-containing antioxidant proteins: new targets for chemotherapy in prostate cancer.
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批准号:nhmrc : 404119
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项目类别:Early Career Fellowships
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资助金额:$12.82万
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财政年份:2006
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负责人:A/Pr Aleksandra Filipovska
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依托单位:
国内基金
海外基金
功能有机配体新颖设计与有机金属超分子导向组装
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批准号:20772152
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项目类别:面上项目
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资助金额:28.0万元
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批准年份:2007
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负责人:于澍燕
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依托单位: