Refrigerated centrifuge

冷冻离心机

• 批准号: 374566-2009
• 负责人: Blay, Jonathan
• 金额: $ 1.32万
• 依托单位: Dalhousie University
• 依托单位国家: 加拿大
• 项目类别: Research Tools and Instruments - Category 1 (<$150,000)
• 财政年份: 2008
• 资助国家: 加拿大
• 起止时间: 2008-01-01 至 2009-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=411961
• 关键词: Refrigerated; centrifuge

Our research is in cell biology, and addresses how cells behave when they divide and move. We measure cell growth, changes in cell size, and the levels and functions of different proteins that are important to the cell. Most of our work involves cells that are first grown in culture and then manipulated in various ways to address the questions that we wish to answer. A central part of all of our research is to be able to handle the cells as we concentrate them in their growth media, expose them to different reagents in a liquid environment, or wash them free of materials to which they have been exposed. For this we need a centrifuge that is able to sediment ('spin down') the cells while keeping them cool and able to survive unharmed by the experience. Our existing machine is nearly 20 years old and at the end of its life. We need to replace it urgently and add certain functions that are now necessary for our work. This piece of equipment will play a central role in all that we do in our research, and will be a sound investment as part of our NSERC-funded quest for knowledge.

我们的研究是在细胞生物学，并解决如何细胞行为时，他们分裂和移动。我们测量细胞生长，细胞大小的变化，以及对细胞重要的不同蛋白质的水平和功能。我们的大部分工作都涉及首先在培养中生长的细胞，然后以各种方式进行操作，以解决我们希望回答的问题。我们所有研究的一个核心部分是能够处理细胞，因为我们将它们集中在生长培养基中，将它们暴露在液体环境中的不同试剂中，或者将它们从暴露的材料中清洗出来。为此，我们需要一个离心机，它能够沉淀（“旋转”）细胞，同时保持它们冷却，并能够在经历中不受伤害地生存。我们现有的机器已经使用了近20年，处于使用寿命的尽头。我们需要紧急更换它，并增加我们工作所必需的某些功能。这台设备将在我们的研究中发挥核心作用，并将成为我们NSERC资助的知识追求的一部分。