Targeting the Pathophysiology and Therapy of Liver Fibrosis

针对肝纤维化的病理生理学和治疗

• 批准号: nhmrc : 1004517
• 负责人: A/Pr Julie Jonsson
• 金额: $ 32.27万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/targeting-pathophysiology-therapy-liver-fibrosis/109042
• 关键词: Targeting; Pathophysiology; Therapy; Liver; Fibrosis

Hepatic fibrosis, or scarring of the liver, is a serious condition which can lead to liver cancer or death. Treatment of liver scarring is currently not effective once the scarring is well developed. This project aims to examine agents which may act to halt liver scarring once it has already developed. Outcomes from this project may help provide potential treatments to reduce the need for liver transplantation or to reduce patient deaths.

肝纤维化或肝脏疤痕是一种严重的疾病，可能导致肝癌或死亡。目前，一旦疤痕形成良好，治疗肝脏疤痕就不再有效。这个项目的目的是研究一旦肝疤痕形成，可以阻止其形成的药物。该项目的成果可能有助于提供潜在的治疗方法，以减少对肝移植的需求或减少患者死亡。