Targeting the Pathophysiology and Therapy of Liver Fibrosis
Targeting the Pathophysiology and Therapy of Liver Fibrosis
批准号:
nhmrc : 1004517
负责人:
A/Pr Julie Jonsson
金额:
$32.27万
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2011
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2011-01-01 至 2013-12-31
中文摘要
肝纤维化或肝脏瘢痕形成是一种严重的疾病,可导致肝癌或死亡。一旦瘢痕形成发展良好,目前对肝瘢痕形成的治疗是无效的。这个项目的目的是检查可能采取行动,以阻止肝脏疤痕一旦它已经发展。该项目的结果可能有助于提供潜在的治疗方法,以减少对肝移植的需求或减少患者死亡。
英文摘要
Hepatic fibrosis, or scarring of the liver, is a serious condition which can lead to liver cancer or death. Treatment of liver scarring is currently not effective once the scarring is well developed. This project aims to examine agents which may act to halt liver scarring once it has already developed. Outcomes from this project may help provide potential treatments to reduce the need for liver transplantation or to reduce patient deaths.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Monocytes/macrophages in chronic liver diseases: cross-talk with hepatocytes and nonparenchymal cells and role in progressive liver injury
-
批准号:nhmrc : 1003108
-
项目类别:NHMRC Project Grants
-
资助金额:$39.92万
-
财政年份:2011
-
负责人:A/Pr Julie Jonsson
-
依托单位:
Role of obesity in impaired treatment response in chronic hepatitis C: mechanisms and therapeutic strategies
-
批准号:nhmrc : 511201
-
项目类别:NHMRC Project Grants
-
资助金额:$36.01万
-
财政年份:2008
-
负责人:A/Pr Julie Jonsson
-
依托单位:
Hepatocyte replicative arrest, hepatic progenitor cells and the ductular reaction in hepatic fibrogenesis
-
批准号:nhmrc : 455985
-
项目类别:NHMRC Project Grants
-
资助金额:$35.19万
-
财政年份:2007
-
负责人:A/Pr Julie Jonsson
-
依托单位:
The role of steatosis in promoting cellular injury and fibrogenesis in human liver disease
-
批准号:nhmrc : 351579
-
项目类别:NHMRC Project Grants
-
资助金额:$27.63万
-
财政年份:2005
-
负责人:A/Pr Julie Jonsson
-
依托单位:
Novel genes and protein in non-alcoholic fatty liver disease: potential basis of a serum-based assessment of disease sta
-
批准号:nhmrc : 252974
-
项目类别:NHMRC Development Grants
-
资助金额:$13.34万
-
财政年份:2003
-
负责人:A/Pr Julie Jonsson
-
依托单位:
Investigation of the role of the Renin-Angiotensin System in hepatic fibrosis.
-
批准号:nhmrc : 210109
-
项目类别:NHMRC Project Grants
-
资助金额:$16.47万
-
财政年份:2002
-
负责人:A/Pr Julie Jonsson
-
依托单位:
DEVELOPMENT OF CLINICALLY APPLICABLE STRATEGIES TO INDUCE AND MONITOR LONG TERM ACCEPTANCE OF LIVER ALLOGRAFTS
-
批准号:nhmrc : 142608
-
项目类别:NHMRC Project Grants
-
资助金额:$19.14万
-
财政年份:2001
-
负责人:A/Pr Julie Jonsson
-
依托单位:
海外基金