Structure and dynamics of aerosols and nanoparticles

气溶胶和纳米颗粒的结构和动力学

• 批准号: 355869-2008
• 负责人: Signorell, Ruth
• 金额: $ 3.79万
• 依托单位: University of British Columbia
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2009
• 资助国家: 加拿大
• 起止时间: 2009-01-01 至 2010-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=431806
• 关键词: Structure; dynamics; aerosols; nanoparticles

The rapidly growing interest in molecular nanoparticles, aerosols, and clusters with diameters ranging from subnanometers to microns arises from their increasing relevance in many different fields. Molecular particles of widely varying composition are seen to play an important role, e. g. as aerosols in atmospheric processes or as reactive sites in interstellar dust. In this context it is obviously crucial to know the chemical composition, the size, and the reactivity of these particles and to understand the processes by which they are formed. The ability to control their formation is not only a prerequisite for laboratory studies, but also opens up other fields of application such as nanoparticles of pharmaceutical agents. The major goal here is the preparation of encapsulated or coated drug particles for controlled or even targeted drug delivery in medical applications.

对直径从亚纳米到微米的分子纳米颗粒、气溶胶和团簇的兴趣迅速增长，这是因为它们在许多不同领域的相关性越来越大。组成成分变化很大的分子颗粒被认为起着重要的作用，例如。G.作为大气过程中的气溶胶或星际尘埃中的反应场所。在这种情况下，了解这些颗粒的化学组成、大小和反应性以及了解它们形成的过程显然是至关重要的。控制其形成的能力不仅是实验室研究的先决条件，而且还开辟了其他应用领域，如药物制剂的纳米颗粒。这里的主要目标是制备用于医疗应用中的受控或甚至靶向药物递送的包封或包衣药物颗粒。