Understanding the Assembly of Poxvirus Immature Particles

了解痘病毒未成熟颗粒的组装

• 批准号: nhmrc : 606597
• 负责人: A/Pr Fasseli Coulibaly
• 金额: $ 21.06万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2010
• 资助国家: 澳大利亚
• 起止时间: 2010-01-01 至 2012-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/understanding-assembly-poxvirus-immature-particles/100947
• 关键词: Understanding; Assembly; Poxvirus; Immature; Particles

Smallpox is an ancient and dreadful disease that enormously influenced human history causing over 300 millions of deaths in the 20th century only. Human cases of monkeypox virus in the US and the potential use of smallpox as a bioterrorism weapon have called for an urgent improvement in Australia's preparedness against poxviruses. We investigate the assembly of these viruses to advance our fundamental understanding of poxvirus biology and provide rationally designed drugs to fight them off.

天花是一种古老而可怕的疾病，它对人类历史产生了巨大的影响，仅在世纪就造成3亿多人死亡。美国的猴痘病毒人间病例和天花作为生物恐怖主义武器的潜在用途，要求澳大利亚紧急改善对痘病毒的准备。我们研究这些病毒的组装，以推进我们对痘病毒生物学的基本理解，并提供合理设计的药物来对抗它们。