Understanding axonal fusion: an alternative mechanism to repair injured axons.
Understanding axonal fusion: an alternative mechanism to repair injured axons.
批准号:
nhmrc : GNT1129367
负责人:
A/Pr Massimo Hilliard
金额:
$64.84万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2017
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2017-01-01 至 --
中文摘要
能够通过将两个损伤部分缝合在一起来修复受损神经是神经外科中的一个令人难以置信的挑战,并且对于外科医生以及患有脊髓或外周损伤的患者来说是非常期望的结果。我们已经发现了通过促进两个分离片段的重新连接来介导神经修复的分子。我们将研究它们的功能,以及它们是否可以用于修复受损的哺乳动物神经元。
英文摘要
Being able to repair an injured nerve by stitching the two damages sections back together is an incredible challenge in neurosurgery, and a highly desired outcome for the surgeon as well as for the patient suffering a spinal cord or peripheral injury. We have discovered molecules that mediate nerve repair by favouring the reconnection of the two separated fragments. We will study how they function, and if they can be applied to repair injured mammalian neurons.
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会议论文
Identification and study of novel conserved molecule with an axonal protective function
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批准号:nhmrc : GNT1145896
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项目类别:Project Grants
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资助金额:$62.5万
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财政年份:2018
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负责人:A/Pr Massimo Hilliard
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依托单位:
Identification and study of novel conserved molecule with an axonal protective function
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批准号:nhmrc : 1145896
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项目类别:Project Grants
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资助金额:$42.26万
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财政年份:2018
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负责人:A/Pr Massimo Hilliard
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依托单位:
Understanding axonal fusion: an alternative mechanism to repair injured axons.
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批准号:nhmrc : 1129367
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项目类别:Project Grants
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资助金额:$44.25万
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财政年份:2017
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负责人:A/Pr Massimo Hilliard
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依托单位:
Epigenetic determination of neuronal vulnerability and neurodegenerative disease
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批准号:nhmrc : 1128381
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项目类别:Project Grants
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资助金额:$42.17万
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财政年份:2017
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负责人:A/Pr Massimo Hilliard
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依托单位:
Epigenetic determination of neuronal vulnerability and neurodegenerative disease
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批准号:nhmrc : GNT1128381
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项目类别:Project Grants
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资助金额:$61.79万
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财政年份:2017
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负责人:A/Pr Massimo Hilliard
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依托单位:
Axonal regeneration and degeneration: cellular and molecular mechanisms
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批准号:nhmrc : GNT1111042
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项目类别:Research Fellowships
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资助金额:$62.27万
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财政年份:2016
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负责人:A/Pr Massimo Hilliard
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依托单位:
The role of membrane phospholipids in regenerative axonal fusion
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批准号:nhmrc : GNT1101974
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项目类别:Project Grants
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资助金额:$57.2万
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财政年份:2016
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负责人:A/Pr Massimo Hilliard
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依托单位:
Axonal regeneration and degeneration: cellular and molecular mechanisms
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批准号:nhmrc : 1111042
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项目类别:Research Fellowships
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资助金额:$42.93万
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财政年份:2016
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负责人:A/Pr Massimo Hilliard
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依托单位:
The role of membrane phospholipids in regenerative axonal fusion
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批准号:nhmrc : 1101974
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项目类别:Project Grants
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资助金额:$39.22万
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财政年份:2016
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负责人:A/Pr Massimo Hilliard
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依托单位:
Axonal fusion to promote nerve repair: molecules and mechanisms.
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批准号:nhmrc : 1068871
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项目类别:Project Grants
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资助金额:$30.42万
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财政年份:2014
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负责人:A/Pr Massimo Hilliard
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依托单位:
Understanding the role of TDP-43 in motor neuron disease.
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批准号:nhmrc : 1067461
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项目类别:Project Grants
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资助金额:$43.61万
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财政年份:2014
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负责人:A/Pr Massimo Hilliard
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依托单位:
Membrane fusion in axonal regeneration: molecules and mechanisms
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批准号:nhmrc : 631634
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项目类别:NHMRC Project Grants
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资助金额:$30.78万
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财政年份:2010
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负责人:A/Pr Massimo Hilliard
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依托单位:
Discovering molecules and mechanisms regulating dendrite formation
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批准号:nhmrc : 631605
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项目类别:NHMRC Project Grants
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资助金额:$34.54万
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财政年份:2010
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负责人:A/Pr Massimo Hilliard
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依托单位:
Axonal degeneration in C. elegans neurons
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批准号:nhmrc : 569500
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项目类别:NHMRC Project Grants
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资助金额:$34.09万
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财政年份:2009
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负责人:A/Pr Massimo Hilliard
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依托单位:
国内基金
海外基金
神经细丝磷酸化调控慢向轴突运输及轴突形态的理论研究
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批准号:31601145
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项目类别:青年科学基金项目
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资助金额:20.0万元
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批准年份:2016
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负责人:李印贇
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依托单位: