The role of membrane phospholipids in regenerative axonal fusion

膜磷脂在再生轴突融合中的作用

• 批准号: nhmrc : GNT1101974
• 负责人: A/Pr Massimo Hilliard
• 金额: $ 57.2万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/role-membrane-phospholipids-axonal-fusion/1346186
• 关键词: role; membrane; phospholipids; regenerative; axonal

Injuries to the nervous system can cause lifelong disabilities due to ineffective repair of the damaged nerve fibres. Our previous research has identified a highly efficient mechanism that occurs in nematode worms that allows severed nerves to fuse back together. We will now focus on understanding precisely how this mechanism works, and investigate its utility in repairing nerves that don’t normally utilise this repair mechanism.

神经系统的损伤可能会导致终生残疾，因为受损的神经纤维修复不力。我们之前的研究发现了一种发生在线虫身上的高效机制，它允许切断的神经融合在一起。我们现在将专注于准确地了解这种机制是如何工作的，并研究它在修复通常不使用这种修复机制的神经方面的效用。