Understanding the role of TDP-43 in motor neuron disease.
Understanding the role of TDP-43 in motor neuron disease.
批准号:
nhmrc : 1067461
负责人:
A/Pr Massimo Hilliard
金额:
$43.61万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2014
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2014-01-01 至 2016-12-31
中文摘要
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英文摘要
Motor neuron disease (MND) is a fatal neurodegenerative disease with no cure. The cause of MND is poorly understood but new research has shown that defects in TDP-43, an RNA binding protein involved in gene regulation, can lead to the disease. This project is aimed at discovering the molecular mechanisms of TDP-43 function, which will improve the understanding of the disease and aid in the development of new therapies.
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