Understanding the developmental basis of kidney disease

了解肾脏疾病的发育基础

• 批准号: nhmrc : GNT1106516
• 负责人: Prof Ian Smyth
• 金额: $ 62.27万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Research Fellowships
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/understanding-developmental-basis-kidney-disease/1346519
• 关键词: Understanding; developmental; basis; kidney; disease

Kidney disease is a considerable burden on the health system and much of it derives from events that occur during organ development. In this grant I will investigate why human nephron number varies between people, how renal cysts form and what genes are mutated in patients with congenital kidney malformations.

肾脏疾病是卫生系统的一个相当大的负担，其中大部分来自器官发育过程中发生的事件。在这项资助中，我将研究为什么人与人之间的肾单位数量不同，肾囊肿是如何形成的，以及先天性肾畸形患者的基因突变。