The cellular basis of branching morphogenesis during kidney development

肾脏发育过程中分支形态发生的细胞基础

• 批准号: DP190101037
• 负责人: Prof Ian Smyth
• 金额: $ 47.73万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2019
• 资助国家: 澳大利亚
• 起止时间: 2019-08-01 至 2022-07-30
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP190101037
• 关键词: cellular; basis; branching; morphogenesis; during

This project aims to study the process of branching morphogenesis which drives the development of the kidney. Previous studies group have demonstrated, in general terms, how branching progresses during gestation. However, little is known about the fundamental cellular events which trigger or characterise this basic developmental process. This project expects to provide deep insights into the cellular basis of tissue and organ development. In studying this process the project should provide critical insights into how cells act, individually and collectively, to build tissues.

该项目旨在研究驱动肾脏发育的分支形态发生过程。之前的研究小组已经证明了妊娠期间分支是如何进展的。然而，人们对触发或表征这一基本发育过程的基本细胞事件知之甚少。该项目期望为组织和器官发育的细胞基础提供深入的见解。在研究这一过程时，该项目应该提供关于细胞如何单独和集体地构建组织的重要见解。