Understanding the role of endogenous and pharmacologic glycosaminoglycans in preventing pre-eclampsia

了解内源性和药理学糖胺聚糖在预防先兆子痫中的作用

• 批准号: nhmrc : 1042239
• 负责人: A/Pr Joanne Said
• 金额: $ 34.45万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/understanding-role-endogenous-pre-eclampsia/111445
• 关键词: Understanding; role; endogenous; pharmacologic; glycosaminoglycans

Pre-eclampsia (PE) is a serious pregnancy complication that affects the well being of the mother and baby. There is no cure for PE except for delivery of the baby. This may result in delivery much earlier than expected causing a very premature baby. This study investigates substances in the placenta that may be responsible for causing PE. If we can understand how these substances cause the problem of PE, we may be able to find better ways of treating or preventing it.

先兆子痫（PE）是一种严重的妊娠并发症，影响母亲和婴儿的健康。除了分娩，PE没有治愈的方法。这可能会导致分娩比预期早得多，导致早产儿。这项研究调查了胎盘中可能导致PE的物质。如果我们能够了解这些物质是如何导致PE问题的，我们可能能够找到更好的治疗或预防方法。