A unique network of phagocytic cells at the interface between the liver and peritoneal cavity

肝脏和腹膜腔界面处独特的吞噬细胞网络

• 批准号: nhmrc : GNT1108565
• 负责人: A/Pr David Bowen
• 金额: $ 78.75万
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/unique-network-phagocytic-peritoneal-cavity/1346651
• 关键词: unique; network; phagocytic; cells; interface

This project aims to characterise the nature and ontogeny of a novel population of cells with phagocytic capacity that forms a network underlying the capsule of mouse and human liver reminiscent of that formed by Langherans cells in the epidermis of the skin. In this project we will characterise this newly described liver capsular macrophage subset, define their ontogeny and assess their specific functions.

该项目旨在描述一种具有吞噬能力的新型细胞群的性质和个体发生，这种细胞群在小鼠和人类肝脏的包膜下形成一个网络，让人想起皮肤表皮中的朗格朗细胞。在这个项目中，我们将描述这种新描述的肝包膜巨噬细胞亚群，定义它们的个体发生并评估它们的特定功能。