The molecular basis of zinc toxicity to Gram-positive bacteria

锌对革兰氏阳性菌毒性的分子基础

• 批准号: DP120103957
• 负责人: Prof Christopher McDevitt
• 金额: $ 18.3万
• 依托单位: The University of Adelaide
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-01-01 至 2015-06-30
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP120103957
• 关键词: molecular; basis; zinc; toxicity; Gram

Gram-positive bacteria are a major cause of infectious diseases in both developed and developing countries. This project will contribute to our understanding of how zinc causes toxicity to these bacteria and facilitate our exploitation of this Achilles heel, by providing new insights into fundamental aspects of microbial physiology.

革兰氏阳性菌是发达国家和发展中国家传染病的主要原因。该项目将有助于我们了解锌如何对这些细菌产生毒性，并通过提供对微生物生理学基本方面的新见解来促进我们对这一致命弱点的利用。