High speed, low noise, direct detection X-ray imagers for medical imaging applications

适用于医学成像应用的高速、低噪声、直接检测 X 射线成像仪

• 批准号: 365162-2008
• 负责人: Karim, Karim
• 金额: $ 8.75万
• 依托单位: University of Waterloo
• 依托单位国家: 加拿大
• 项目类别: Strategic Projects - Group
• 财政年份: 2010
• 资助国家: 加拿大
• 起止时间: 2010-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=460917
• 关键词: speed; low; noise; direct; detection

New x-ray radiographic systems based on amorphous silicon digital flat panel technology have revolutionized our capability of producing digital x-ray radiographic images. Amorphous selenium direct-detection X-ray detectors used in these systems provide the best spatial resolution and are predominantly used in the mammography market However, the selenium detector is coupled to an amorphous silicon pixel readout circuit which is inherentty noisy, therefore there is a trade-off between fine image detail and image contrast for low dose, real-time applications. The goal of this research project is to develop a digital imager that provides higher signal-to-noise ratio (SNR) in fast frame rate applications while preserving fine image detail, for example, in 3D diagnostic imaging of breast cancer (mammography tomosynthesis). The primary benefits of improving digrtal X-ray imaging technology include reduction of diagnostic error and better detection of cancer. In addition, a reduction in radiation dose, while maintaining or enhancing detector performance, is an important competitive advantage. The results of this research are expected to help realize a mammography tomosynthesis product in the 5*10 year time rrame that will directly benefit the Canadian economy. The research will also involve the training of future scientists and engineers in the photonics, manufacturing, and information technology industries. Such highly skilled personnel are essential to maintain Canada's technological advantage internationally.

基于非晶硅数字平板技术的新型X射线照相系统彻底改变了我们制作数字X射线照相图像的能力。在这些系统中使用的非晶硒直接检测X射线探测器提供最佳的空间分辨率，并且主要用于乳房X射线摄影市场。然而，硒探测器耦合到具有固有噪声的非晶硅像素读出电路，因此对于低剂量实时应用，在精细图像细节和图像对比度之间存在折衷。该研究项目的目标是开发一种数字成像仪，在快速帧率应用中提供更高的信噪比（SNR），同时保留精细的图像细节，例如，在乳腺癌的3D诊断成像（乳腺X射线断层合成）中。改进数字X射线成像技术的主要好处包括减少诊断错误和更好地检测癌症。此外，减少辐射剂量，同时保持或提高探测器性能，是一个重要的竞争优势。这项研究的结果预计将有助于在5*10年的时间范围内实现乳腺X射线断层合成产品，这将直接有利于加拿大经济。该研究还将涉及光子学，制造业和信息技术行业未来科学家和工程师的培训。这些高技能人才对保持加拿大在国际上的技术优势至关重要。