High speed, low noise, direct detection X-ray imagers for medical imaging applications

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New x-ray radiographic systems based on amorphous silicon digital flat panel technology have revolutionized our capability of producing digital x-ray radiographic images. Amorphous selenium direct-detection X-ray detectors used in these systems provide the best spatial resolution and are predominantly used in the mammography market However, the selenium detector is coupled to an amorphous silicon pixel readout circuit which is inherentty noisy, therefore there is a trade-off between fine image detail and image contrast for low dose, real-time applications. The goal of this research project is to develop a digital imager that provides higher signal-to-noise ratio (SNR) in fast frame rate applications while preserving fine image detail, for example, in 3D diagnostic imaging of breast cancer (mammography tomosynthesis). The primary benefits of improving digrtal X-ray imaging technology include reduction of diagnostic error and better detection of cancer. In addition, a reduction in radiation dose, while maintaining or enhancing detector performance, is an important competitive advantage. The results of this research are expected to help realize a mammography tomosynthesis product in the 5*10 year time rrame that will directly benefit the Canadian economy. The research will also involve the training of future scientists and engineers in the photonics, manufacturing, and information technology industries. Such highly skilled personnel are essential to maintain Canada's technological advantage internationally.