Request for an upgrade to existing AFM to significantly improve the soft imaging capability and future upgradability

请求对现有 AFM 进行升级，以显着提高软成像能力和未来的可升级性

• 批准号: 406713-2011
• 负责人: Bizzotto, Dan
• 金额: $ 10.89万
• 依托单位: University of British Columbia
• 依托单位国家: 加拿大
• 项目类别: Research Tools and Instruments - Category 1 (<$150,000)
• 财政年份: 2010
• 资助国家: 加拿大
• 起止时间: 2010-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=472543
• 关键词: Request; upgrade; existing; AFM; significantly

The request for an upgrade to the existing 10 year old AFM will replace an aging instrument that is no-longer supported and quickly losing ground to the newer more stable and user friendly equipment. The upgrade will allow for more reliable imaging of difficult sensitive samples using magnetically driven tapping mode (known as MAC mode) with the added ability of being able to direct the tip to the area of interest on the sample. This video access was not available 10 years ago, and has been one of the limitations that has led to the decline in the use of the AFM. We have successfully used MAC Mode to characterize Pt and Pt-alloy nanoparticles on a carbon support, illustrating the ability of this method to characterize difficult samples. That said, the new model will enable even more delicate samples to be investigated, specifically modified electrode surfaces containing DNA or adsorbed liposomes. Our attempts to image these surfaces with our current instrument have been less reliable. Performing these measurements in liquid or in electrochemical environments is also quite limiting. The requested instrument is a newer design which has solved a number of the alignment and sealing issues and will significantly enhance our ability to perform these measurements in liquid.

升级现有10年的AFM的请求将取代不再支持的老化仪器，并迅速失去对更新的更稳定和用户友好的设备的支持。此次升级将允许使用磁驱动轻敲模式（称为MAC模式）对困难的敏感样本进行更可靠的成像，并增加了能够将尖端引导到样本上感兴趣区域的能力。这种视频访问在10年前是不可用的，并且一直是导致AFM使用减少的限制之一。我们已经成功地使用MAC模式来表征碳载体上的Pt和Pt合金纳米颗粒，说明了这种方法表征困难样品的能力。也就是说，新模型将能够研究更精细的样品，特别是含有DNA或吸附脂质体的修饰电极表面。我们试图用我们现有的仪器对这些表面进行成像，但不太可靠。在液体或电化学环境中进行这些测量也是非常有限的。所要求的仪器是一种较新的设计，它解决了一些对准和密封问题，并将大大提高我们在液体中进行这些测量的能力。