Toward understanding the molecular mechanisms that regulate intermediate filament keratin functions in hepatocytes
Toward understanding the molecular mechanisms that regulate intermediate filament keratin functions in hepatocytes
批准号:
195539-2011
负责人:
Cadrin, Monique
金额:
$2.19万
依托单位国家:
加拿大
项目类别:
Discovery Grants Program - Individual
财政年份:
2011
资助国家:
加拿大
项目状态:
已结题
起止时间:
2011-01-01 至 2012-12-31
中文摘要
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英文摘要
Intermediate filaments (IFs) are with microtubules and actin microfilaments the major cytoskeletal components of most mammalian cells. Modifications in K8/18 IFs organization and formation of keratin containing aggregates called Mallory-Denk bodies are common to many human chronic liver diseases such as alcoholic hepatitis, Wilson's disease and liver steatosis in obesity. Recent studies have shown evidences that K8/18 play an important role in the protection of hepatocytes against chronic stress-induced liver injuries.
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Keratin intermediate filaments: a dynamic framework for major signaling molecules involved in epithelial cell survival and cell death
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批准号:RGPIN-2016-05735
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.26万
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财政年份:2021
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负责人:Cadrin, Monique
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依托单位:
Keratin intermediate filaments: a dynamic framework for major signaling molecules involved in epithelial cell survival and cell death
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批准号:RGPIN-2016-05735
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.26万
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财政年份:2020
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负责人:Cadrin, Monique
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依托单位:
Keratin intermediate filaments: a dynamic framework for major signaling molecules involved in epithelial cell survival and cell death
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批准号:RGPIN-2016-05735
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.26万
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财政年份:2019
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负责人:Cadrin, Monique
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依托单位:
Keratin intermediate filaments: a dynamic framework for major signaling molecules involved in epithelial cell survival and cell death
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批准号:RGPIN-2016-05735
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.26万
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财政年份:2018
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负责人:Cadrin, Monique
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依托单位:
Keratin intermediate filaments: a dynamic framework for major signaling molecules involved in epithelial cell survival and cell death
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批准号:RGPIN-2016-05735
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.26万
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财政年份:2017
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负责人:Cadrin, Monique
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依托单位:
Keratin intermediate filaments: a dynamic framework for major signaling molecules involved in epithelial cell survival and cell death
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批准号:RGPIN-2016-05735
-
项目类别:Discovery Grants Program - Individual
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资助金额:$2.26万
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财政年份:2016
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负责人:Cadrin, Monique
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依托单位:
Toward understanding the molecular mechanisms that regulate intermediate filament keratin functions in hepatocytes
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批准号:195539-2011
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.19万
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财政年份:2015
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负责人:Cadrin, Monique
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依托单位:
Toward understanding the molecular mechanisms that regulate intermediate filament keratin functions in hepatocytes
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批准号:195539-2011
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.19万
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财政年份:2014
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负责人:Cadrin, Monique
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依托单位:
Toward understanding the molecular mechanisms that regulate intermediate filament keratin functions in hepatocytes
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批准号:195539-2011
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.19万
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财政年份:2013
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负责人:Cadrin, Monique
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依托单位:
Toward understanding the molecular mechanisms that regulate intermediate filament keratin functions in hepatocytes
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批准号:195539-2011
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.19万
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财政年份:2012
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负责人:Cadrin, Monique
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依托单位:
How do keratins protect hepatocytes against toxic stress
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批准号:195539-2007
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项目类别:Discovery Grants Program - Individual
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资助金额:$1.89万
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财政年份:2009
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负责人:Cadrin, Monique
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依托单位:
How do keratins protect hepatocytes against toxic stress
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批准号:195539-2007
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项目类别:Discovery Grants Program - Individual
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资助金额:$1.89万
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财政年份:2008
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负责人:Cadrin, Monique
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依托单位:
How do keratins protect hepatocytes against toxic stress
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批准号:195539-2007
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项目类别:Discovery Grants Program - Individual
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资助金额:$1.89万
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财政年份:2007
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负责人:Cadrin, Monique
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依托单位:
How does keratin protect hepatocytes against hepatotoxins?
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批准号:195539-2004
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项目类别:Discovery Grants Program - Individual
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资助金额:$1.82万
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财政年份:2006
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负责人:Cadrin, Monique
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依托单位:
How does keratin protect hepatocytes against hepatotoxins?
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批准号:195539-2004
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项目类别:Discovery Grants Program - Individual
-
资助金额:$1.82万
-
财政年份:2005
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负责人:Cadrin, Monique
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依托单位:
How does keratin protect hepatocytes against hepatotoxins?
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批准号:195539-2004
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项目类别:Discovery Grants Program - Individual
-
资助金额:$1.82万
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财政年份:2004
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负责人:Cadrin, Monique
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依托单位:
Keratin regulation and response of hepatocytes to hepatotoxins
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批准号:195539-2000
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项目类别:Discovery Grants Program - Individual
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资助金额:$1.82万
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财政年份:2003
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负责人:Cadrin, Monique
-
依托单位:
Keratin regulation and response of hepatocytes to hepatotoxins
-
批准号:195539-2000
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$1.82万
-
财政年份:2002
-
负责人:Cadrin, Monique
-
依托单位:
Keratin regulation and response of hepatocytes to hepatotoxins
-
批准号:195539-2000
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$1.82万
-
财政年份:2001
-
负责人:Cadrin, Monique
-
依托单位:
Keratin regulation and response of hepatocytes to hepatotoxins
-
批准号:195539-2000
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$1.82万
-
财政年份:2000
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负责人:Cadrin, Monique
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依托单位:
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