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Virus-host interactions: induction of cytotoxic T cells immune responses via the direct and alternative MHC class I presentation pathways

Virus-host interactions: induction of cytotoxic T cells immune responses via the direct and alternative MHC class I presentation pathways
病毒-宿​​主相互作用:通过直接和替代 MHC I 类呈递途径诱导细胞毒性 T 细胞免疫反应
批准号:
311779-2010
负责人:
Basta, Sameh
金额:
$1.97万
依托单位:
依托单位国家:
加拿大
项目类别:
Discovery Grants Program - Individual
财政年份:
2011
资助国家:
加拿大
项目状态:
已结题
起止时间:
2011-01-01 至 2012-12-31

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中文摘要
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英文摘要
During virus infections, the immune system utilizes various defense elements that interact together to clear the infection. A central aspect in understanding host immunity to virus infections focuses on the interaction of the virus with host immune cells such as the macrophages and dendritic cells. These cells are known as professional antigen-presenting cells (pAPCs) because they present molecules from the virus on their cell surface and initiate the activation of cytotoxic killer cells.
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