Flow Cytometry Cell Sorting Analysis Research Platform.

荧光活化细胞分选（FACS）通常用于从异质细胞悬浮液中富集特定细胞类型。FACS分选依赖于荧光标记抗体与特定生物标志物（如细胞表面的受体）的结合。由激光发射激活的荧光特性很容易识别感兴趣的细胞，并允许它们以特殊的纯度分离。这是一种有效和快速的方法来分离许多生物细胞类型，并将催化我们正在进行的生物研究的更深层次，旨在整合细胞内信号事件与特定细胞类型的功能。双激光索尼SH800高速FACS与生物安全柜要求支持nserc资助的研究工作，在和细胞生物学，遗传学，生物技术，感染，免疫和炎症领域。该设备将对需要生物危害II级隔离的细胞进行分类，这是女王大学目前没有的功能。生物安全特性对于限制高素质人员（HQP）接触传染原和保持收集后用于移植或培养的生物样品的完整性至关重要。

Fluorescence Activated Cell Sorting (FACS) is routinely used to enrich for a specific cell type from a heterogeneous cell suspension. FACS sorting relies on the binding of fluorescence-tagged antibodies to specific biomarkers such as receptors on the surface of the cell. The characteristic fluorescent properties activated by laser emissions readily identify cells of interest and permits their separation at exceptional purity. This is an effective and rapid approach to isolate many biological cell types and will catalyze much deeper levels of our ongoing biological research that are aimed at integrating intracellular signaling events with functions in the specific cell types of interest. The dual laser Sony SH800 high-speed FACS with a biosafety cabinet is requested to support NSERC-funded research work in the fields of and cell biology, genetics, biotechnology, infection, immunity, and inflammation. This equipment will sort cells that require biohazard level II containment, a feature not currently available at Queen's University. The biosafety feature is essential to limit the exposure of highly qualified personnel (HQP) to infectious agents and to maintain the integrity of the biological samples for transplantation or culture following collection.