Peptide synthesizer for research in pharmacology and medicinal chemistry. Synthétiseur de peptides pour la recherche en pharmacologie et chimie médicinale.

肽是生物体正常运作所必需的氨基酸的小聚合物。多肽是多种生理功能的信使，包括炎症、疼痛、血糖、血压等。因此，多肽及其相关靶点的结构/功能研究对于了解与许多疾病相关的各种代谢途径的功能至关重要。我们的研究计划需要一个肽合成系统来生产各种肽和进行这些项目所必需的类似物。我们研究计划的一个重要方面是开发用于诊断各种癌症的新工具。我们的生物标志物是肽衍生物修饰，以提供更好的对比医学成像。我们研究计划的另一个重要方面是开发肽工具来研究生物相互作用（蛋白质/蛋白质，蛋白质/肽）。所需的肽合成系统也将用于产生肽库：这是我们的结构/功能研究必不可少的特征。此外，多肽合成器的收购也将为我们提供平行制造几种多肽的可能性；从而提高了我们研究单位的生产力。这个系统对我们的几项研究都很重要；它将使我们能够在药理学和药物化学方面进行最先进的研究。

Peptides are small polymers of amino acids essential for the correct functioning of living organisms. Peptides are messengers for a variety of physiological functions inflammation, pain, glycemia, blood pressure, etc. Consequently, structure/function studies of peptides and their associated targets are of crucial importance to understand the function of various metabolic pathways associated to many diseases. Our research program requires a peptide synthesizer system for the production of the various peptides and analogues necessary to conduct these projects. An important aspect of our research program targets the development of new tools for the diagnostic of various types of cancer. Our biomarkers are peptide derivatives modified to offer a better contrast in medical imaging. Another important aspect of our research program targets the development of peptidic tools to study biological interactions (protein/protein, protein/peptide). The required peptide synthesizer system will also be used to produce peptide libraries: a feature essential for our structure/function studies. Moreover, the acquisition of the peptide synthesizer will also provide us with the possibility to make in parallel several peptides; thus increasing the productivity of our research unit. This system is seminal for several of our studies; it will allow us to pursue our state of the art research in pharmacology and medicinal chemistry.