Upgrade of X-ray diffractometer for small molecules

小分子X射线衍射仪升级

• 批准号: 423501-2012
• 负责人: Müller, Jens
• 金额: $ 10.64万
• 依托单位: University of Saskatchewan
• 依托单位国家: 加拿大
• 项目类别: Research Tools and Instruments - Category 1 (<$150,000)
• 财政年份: 2011
• 资助国家: 加拿大
• 起止时间: 2011-01-01 至 2012-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=495951
• 关键词: Upgrade; ray; diffractometer; small; molecules

The determination of molecular structures plays a crucial role in the development of science and of chemistry in particular. Molecular structures are keys to a deeper understanding of chemistry, which, in turn, is the prerequisite to transform chemical knowledge into technology for the benefit of society. The method of single-crystal X-ray diffraction is the most important method to determine structures of molecular species. This method is of central importance in the area of molecular chemistry and is one of the most important standard methods of characterization to date. The equipment requested will be used to repair and upgrade an existing single-crystal X-ray diffractometer that will be used for research and training of highly qualified personnel. This instrument is located in the Saskatchewan Structural Sciences Centre (SSSC), which is a central facility that serves the scientific community of the University of Saskatchewan (U of S) and other researchers external to the U of S. The existing diffractometer has served approximately 20 research groups in the past. For many research programs the availability of an X-ray diffractometer is essential for their research. This holds true for the seven applicants of this proposal, whose research programs span a wide field from organometallic-, to (bio)organic-, and medicinal chemistry.

分子结构的测定在科学发展中起着至关重要的作用，特别是在化学发展中。分子结构是深入理解化学的关键，而深入理解化学又是将化学知识转化为造福社会的技术的先决条件。单晶X射线衍射法是测定分子物种结构的最重要的方法。该方法在分子化学领域具有核心重要性，是迄今为止最重要的标准表征方法之一。所要求的设备将用于修理和更新一台现有的单晶X射线衍射仪，该仪器将用于研究和培训高素质人员。该仪器位于萨斯喀彻温省结构科学中心（SSSC），这是一个中心设施，为萨斯喀彻温大学（U of S）的科学界和其他研究人员提供服务。现有的衍射仪在过去已经为大约20个研究小组服务。对于许多研究项目来说，X射线衍射仪的可用性对于他们的研究至关重要。这适用于该提案的七个申请人，他们的研究项目涵盖了从有机金属化学到（生物）有机化学和药物化学的广泛领域。