Smart & automatic analysis of ocular nystagmus for tracking patients and astronaut health.

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• 批准号: 437383-2012
• 负责人: Galiana, Henrietta
• 金额: $ 8.95万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 项目类别: Idea to Innovation
• 财政年份: 2012
• 资助国家: 加拿大
• 起止时间: 2012-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=499048
• 关键词: Smart; automatic; analysis; ocular; nystagmus

The second most frequent complaint bringing patients to medical clinics or hospital ERs is dizziness or nausea (~1,400 patients/yr at just one McGill hospital). There are many causes of these symptoms: we focus on new tools to evaluate sensory deficits. Signals from vestibular sensors in the inner ear (head motion), and from the retina (visual goals), co-drive brain circuits that control balance and eye movements. The functional limits of responses to vestibular and visual stimuli are measured with eye recordings, but methods to test ocular reflexes have not changed for decades, using large and expensive equipment, and analyzing eye records with subjective criteria incompatible with current neuro-scientific knowledge. Another complication is that ocular reflexes are hybrid responses - switching back and forth between compensation for motion and redirection to a new spatial goal, each with different dynamics. Hence a major impediment for improvement of diagnostic procedures is the lack of modern techniques for automatic classification of nystagmus segments, which restricts feasible test protocols.

第二个最常见的投诉是头晕或恶心（仅麦吉尔一家医院就有约1，400例患者/年）。这些症状的原因有很多：我们专注于评估感觉障碍的新工具。来自内耳前庭传感器（头部运动）和视网膜（视觉目标）的信号共同驱动控制平衡和眼球运动的大脑回路。 对前庭和视觉刺激的反应的功能极限是用眼记录来测量的，但是测试眼反射的方法几十年来没有改变，使用大型和昂贵的设备，并用与当前神经科学知识不相容的主观标准分析眼记录。另一个复杂之处在于，眼反射是混合反应--在补偿运动和重定向到新的空间目标之间来回切换，每种都有不同的动力学。 因此，改善诊断程序的主要障碍是缺乏用于眼震片段自动分类的现代技术，这限制了可行的测试协议。