Development of New Synthons and Catalysts and Applications in Organic Synthesis

新型合成剂和催化剂的开发及其在有机合成中的应用

• 批准号: 194282-2012
• 负责人: McNulty, James
• 金额: $ 3.28万
• 依托单位: McMaster University
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2012
• 资助国家: 加拿大
• 起止时间: 2012-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=514019
• 关键词: Development; New; Synthons; Catalysts; Applications

The project concerns the development of new chemical methods for the manufacture of organic chemicals based upon the use of metal catalysts as well as organic-based catalysts. The objectives are to discover new modes of reactivity of both metal-based catalysts and organic catalysts, including chiral, asymmetric synthesis. These methods are of interest on a fundamental level in exploring new reactions and types of chemical reactivity. Applications of these methods on a practical level towards the production of pharmaceuticals, such as anticancer and antibacterial agents, as well as fine chemicals and substances of interest in the materials fields, such as organic-based photovoltaic materials is the longer term objective.

该项目涉及在使用金属催化剂和有机催化剂的基础上开发制造有机化学品的新化学方法。其目的是发现金属催化剂和有机催化剂的新反应模式，包括手性、不对称合成。这些方法在探索新的化学反应和化学反应类型方面具有重要意义。长期目标是在实际层面上将这些方法应用于药品的生产，如抗癌和抗菌剂，以及精细化学品和材料领域感兴趣的物质，如有机光伏材料。