Development of New Synthons and Catalysts and Applications in Organic Synthesis

新型合成剂和催化剂的开发及其在有机合成中的应用

• 批准号: 194282-2012
• 负责人: McNulty, James
• 金额: $ 3.28万
• 依托单位: McMaster University
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2015
• 资助国家: 加拿大
• 起止时间: 2015-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=569761
• 关键词: Development; New; Synthons; Catalysts; Applications

The project concerns the development of new chemical methods for the manufacture of organic chemicals based upon the use of metal catalysts as well as organic-based catalysts. The objectives are to discover new modes of reactivity of both metal-based catalysts and organic catalysts, including chiral, asymmetric synthesis. These methods are of interest on a fundamental level in exploring new reactions and types of chemical reactivity. Applications of these methods on a practical level towards the production of pharmaceuticals, such as anticancer and antibacterial agents, as well as fine chemicals and substances of interest in the materials fields, such as organic-based photovoltaic materials is the longer term objective.

该项目涉及在使用金属催化剂和有机基催化剂的基础上，为制造有机化学品开发新的化学方法。目的是发现金属基催化剂和有机催化剂的新反应模式，包括手性、不对称合成。这些方法在探索新反应和化学反应类型的基础水平上是有意义的。长期目标是将这些方法应用于生产药物，如抗癌和抗菌剂，以及材料领域的精细化学品和感兴趣的物质，如有机基光伏材料。