Frequency domain mode locked novel dual core fiber laser for multichannel array based doppler optical coherence tomography

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Optical Coherence Tomography (OCT) is a new imaging modality that provides high resolution (near cellular level) suitable for real-time imaging and is becoming available for imaging the retina and other organs for neoplastic and vascular lesions. Doppler OCT (DOCT) adds blood flow imaging capability which is sensitive to slow blood flow in the microcirculation, and has been shown to detect neovasculature in pre-cancer and cancerous conditions. Recently there has been a growing interest in high power cladding pumped fiber lasers such as Yb doped fiber lasers, as a replacement for conventional lasers. Frequency domain mode locking of such fiber lasers may provide an optimal light source for DOCT at a wavelength range of 1027-1105 nm, optimal for imaging biological tissues. We will develop a low-cost and low-maintenance Yb doped fiber laser for multichannel array based DOCT, which could be extremely useful for guiding the next generation laser-based treatments, such as 2-photon photodynamic therapy, and provide a tightly controlled damage radius to preserve normal tissue.