Hydrogel Endovascular Adaptive BioExtrusion System (HEABES) as a new platform for endovascular treatment
Hydrogel Endovascular Adaptive BioExtrusion System (HEABES) as a new platform for endovascular treatment
批准号:
556274-2020
负责人:
Yang, Victor
金额:
$9.11万
依托单位:
依托单位国家:
加拿大
项目类别:
Idea to Innovation
财政年份:
2020
资助国家:
加拿大
项目状态:
已结题
起止时间:
2020-01-01 至 2021-12-31
中文摘要
我们设计了一种新型的血管内水凝胶给药系统。我们的技术水凝胶血管内自适应生物挤出系统(HEABES)是一种基于导管的多材料(水凝胶和/或营养物、生物活性因子、细胞)共挤出设备,可以动态改变物理化学性质,同时保持高时空输送精度,适用于药物输送、组织工程和栓塞术。在这个项目中,我们的目标是进行设计、改进和测试,以证明其在体外和体内的有效性。这项新技术代表了一种更安全、更有效的栓塞、药物输送方法,并有可能成为微创组织工程方法。
英文摘要
We have engineered a new type of endovascular hydrogel delivery system. Our technology, Hydrogel Endovascular Adaptive BioExtrusion System (HEABES), is a catheter-based, multi-material (hydrogels and/or nutrients, bioactive factors, cells) co-extrusion device that can dynamically change physicochemical properties while maintaining high spatiotemporal delivery accuracy, suitable for drug delivery, tissue engineering, and embolization. In this project we aim to perform design refinement and testing to prove its efficacy bot in vitro and in vivo. This new technology represents a safer and more effective method of embolization, drug delivery and potential for minimally invasive tissue engineering approaches.
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会议论文
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负责人:Yang, Victor
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项目类别:Discovery Grants Program - Individual
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