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Translational approach to establish the cardiometabolic health effects and mechanisms of action of fish nutrients: from animal models to obese insulin-resistant subjects

Translational approach to establish the cardiometabolic health effects and mechanisms of action of fish nutrients: from animal models to obese insulin-resistant subjects
建立鱼类营养素对心脏代谢健康影响和作用机制的转化方法:从动物模型到肥胖胰岛素抵抗受试者
批准号:
288805
负责人:
Marette Andr
金额:
$145.7万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2013
资助国家:
加拿大
项目状态:
已结题
起止时间:
2013-01-01 至 2018-01-01

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中文摘要
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英文摘要
Few Canadians meet the weekly recommendations of fish consumption and thus intakes of not only n-3 PUFA but also of fish proteins and vitamin D are low in the general population and even lower in obese subjects. Moreover, many Canadians, especially obese
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Nutrient sensing mechanisms underlying the metabolic effects of dietary proteins in obesity and type 2 diabetes
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    479374
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Role of altered production of branched-chain hydroxy acids (BCHA) in the pathogenesis of type 2 diabetes (T2D) and fatty liver disease and its prevention by BCHA-supplemented yogurt
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Host iNOS dictates gut dysbiosis, bacterial translocation and tissue insulin resistance in murine and human obesity
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Microbiome and liver mechanisms underlying the impact of dietary proteins on obesity and insulin resistance
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    456675
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