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Metabolic functions of the PTPase SHP-1 in insulin target tissues

Metabolic functions of the PTPase SHP-1 in insulin target tissues
PTPase SHP-1 在胰岛素靶组织中的代谢功能
批准号:
239671
负责人:
Marette Andr
金额:
$55.87万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2011
资助国家:
加拿大
项目状态:
已结题
起止时间:
2011-09-01 至 2016-09-01

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中文摘要
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英文摘要
We have recently shown that the protein tyrosine phosphatase SHP-1 is expressed in metabolic tissues and may be involved in the development of obesity-related complications such as type 2 diabetes and fatty liver disease. The main goal of this project is
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Nutrient sensing mechanisms underlying the metabolic effects of dietary proteins in obesity and type 2 diabetes
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  • 财政年份:
    2023
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Role of altered production of branched-chain hydroxy acids (BCHA) in the pathogenesis of type 2 diabetes (T2D) and fatty liver disease and its prevention by BCHA-supplemented yogurt
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    469858
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    $54.89万
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    2022
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Host iNOS dictates gut dysbiosis, bacterial translocation and tissue insulin resistance in murine and human obesity
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    453491
  • 项目类别:
    Operating Grants
  • 资助金额:
    $59.35万
  • 财政年份:
    2021
  • 负责人:
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  • 依托单位:
Microbiome and liver mechanisms underlying the impact of dietary proteins on obesity and insulin resistance
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    456675
  • 项目类别:
    Operating Grants
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    $7.29万
  • 财政年份:
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  • 负责人:
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  • 依托单位:
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