Bioinformatics tool development to analyze and integrate genomics data generated by high-throughput sequencing / Développement d'outils bio-info analysant les données de séquençage

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High-throughput DNA sequencing (HTS) is significantly changing modern biology and is already becoming a very important tool for most laboratories interested in genetics and molecular biology. While advances in HTS technologies continue to improve our ability to collect data, it is becoming increasingly clear that the bottleneck in translating these gains into scientific breakthroughs now resides in data mining and integrative analysis. There is currently no tool exploiting the publicly available epigenomics data sets in order to help understanding new data sets. To fulfill that need, we propose to develop the Genomic Correlator and Enrichment (GeCorE) tool that will be running on a supercomputer and accessible to end users through a web interface. This will allow non-bioinformatician users to benefit from this tool without having to install anything. GeCorE will be using thousands of published whole-genome data sets downloaded, uniformly processed and organized on our server. Through private account, users working on all organisms, thus including many model organisms, will be able to upload their own private epigenomics data and use the GeCorE application to characterize them.