Nanoparticle-mediated highly efficient microfluidic capture and sorting of rare cells

点击翻译按钮获取中文摘要

Circulating tumor cells are shed into the bloodstream by growing tumours. CTCs can be present even when tumours are small and therefore present a promising marker for noninvasive early detection of cancer. We are developing a new device that can isolate these cells and classify their biochemical state. This device may aid in the analysis of tumours using a blood sample collected non-invasively, and its use could eventually lead to the development of improved cancer screening tests. In this project, we are advancing a CTC analysis device to commercialization by re-engineering it to be amenable to high volume manufacturing. We will also integrate a CTC detection system that will be user-friendly and straightforward to automate. With these key advances in hand, we will be ready to pursue commercialization of this device.