Multiscale modeling of fundamental biophysical processes in both dividing and non-dividing cells

分裂和非分裂细胞中基本生物物理过程的多尺度建模

• 批准号: 39827-2013
• 负责人: Tuszynski, Jacek
• 金额: $ 1.82万
• 依托单位: University of Alberta
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2014
• 资助国家: 加拿大
• 起止时间: 2014-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=544844
• 关键词: Multiscale; modeling; fundamental; biophysical; processes

My group's research combines physics, chemistry, biology, computer science, and information science to better understand the role of the cytoskeleton, especially in the context of cancer biology and neuroscience. The key challenge is to develop a consistent modeling framework to transfer data between time and size scales, from molecules to proteins to cells to tissues, accounting for the effects of a single molecular event on the behaviour of a whole cell or tissue.

我的团队的研究结合了物理学，化学，生物学，计算机科学和信息科学，以更好地了解细胞骨架的作用，特别是在癌症生物学和神经科学的背景下。关键的挑战是开发一个一致的建模框架，以在时间和大小尺度之间传输数据，从分子到蛋白质到细胞到组织，解释单个分子事件对整个细胞或组织行为的影响。