Expanding natural product chemical diversity

扩大天然产物化学多样性

• 批准号: 138146-2010
• 负责人: Wright, Gerard
• 金额: $ 5.68万
• 依托单位: McMaster University
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2014
• 资助国家: 加拿大
• 起止时间: 2014-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=545491
• 关键词: Expanding; natural; product; chemical; diversity

Natural products are compounds that are produced by living organisms. These chemicals regulate numerous aspects of cellular life including intra-species (quorum sensing) and inter-species (mutualism, parasitism, etc.) interactions. Furthermore, they are rich sources of toxic molecules that serve producing organisms in infection control (e.g. antibiotics), in capture of prey (e.g. venoms, poisons), and in protection from predators. Given their intrinsic bioactivity and numerous physiological effects, it is not surprising that, natural have served as a rich source of 'natural' medicines and pest control agents for millennia and more recently as drugs and agriculturally important agents and their precursors.

天然产物是由生物体产生的化合物。 这些化学物质调节细胞生命的许多方面，包括物种内（群体感应）和物种间（互利共生，寄生等）。交互. 此外，它们是有毒分子的丰富来源，这些有毒分子在感染控制（例如抗生素）、捕获猎物（例如毒液、毒药）和保护免受捕食者中起作用。 鉴于其固有的生物活性和众多的生理效应，这并不奇怪，天然药物作为“天然”药物和害虫控制剂的丰富来源已有数千年，最近作为药物和农业上重要的试剂及其前体。