Biobutanol production from crude glycerol, the by-product of biodiesel production

拟议项目的目标是开发一种高效的生物丁醇生产工艺，使用细菌发酵和粗甘油作为原料，作为生物柴油工业的低价值副产品。从可再生原料中生物生产丁醇是替代石油燃料和平台化学品的一种有前途的可持续替代方案。在过去的十年里，人们对发酵丁醇的商业兴趣重新抬头(丁胺醇、Gevo、钴等)。使用糖基原料。与此同时，作为生物柴油生产的副产品，粗甘油的供应充足。全球生物柴油产量从2001年的9.59亿升增加到2009年的157.6亿升，复合年增长率为41.9%，每生产10公斤生物柴油产生1公斤甘油。到目前为止，甘油市场还不能接近吸收生物柴油中过剩的粗甘油。细菌菌株(如梭状芽胞杆菌)可以利用粗甘油，高产率地生产丁醇。拟议的项目将利用粗甘油作为原料生产生物丁醇，生物丁醇是一种更高价值的燃料和平台化学品。甘油是目前生物柴油行业的废气。

The goal of the proposed project is to develop an efficient biobutanol production process using bacterial fermentation and crude glycerol as feedstock generated as a low value by-product of the biodiesel industry. Biobased production of butanol from renewable feedstock is a promising and sustainable alternative to substitute petroleum based fuels and platform chemicals. There has been a resurgence of commercial interest in butanol from fermentation in the last decade (Butamax, Gevo, Cobalt, etc.) using sugar-based feedstocks. Meanwhile there is an abundantly available supply of crude glycerol as a byproduct of biodiesel production. The global production of biodiesel increased from 959 million liters in 2001 to 15,760 million liters in 2009, a compounded annual growth rate of 41.9%, generating 1 kg of glycerol for every 10 kg of biodiesel produced. To date the glycerol market cannot come close to absorbing the crude glycerol excess from biodiesel. Strains of bacteria (e.g. Clostridia sp.) can utilize crude glycerol and produce butanol at high yields. The proposed project will utilize crude glycerol, the current waste-stream from the biodiesel industry as a feedstock to produce biobutanol, a higher value fuel and platform chemical.