Biobutanol production from crude glycerol, the by-product of biodiesel production

拟议项目的目标是开发一种高效的生物丁醇生产工艺，使用细菌发酵和粗甘油作为生物柴油工业低价值副产品的原料。从可再生原料生物基生产丁醇是替代石油基燃料和平台化学品的有前途和可持续的替代品。在过去的十年中，对发酵丁醇的商业兴趣重新抬头（Butamax、Gevo、Cobalt等）。使用糖基原料。与此同时，作为生物柴油生产的副产品，粗甘油供应充足。全球生物柴油产量从2001年的9.59亿升增加到2009年的157.6亿升，复合年增长率为41.9%，每生产10公斤生物柴油就产生1公斤甘油。到目前为止，甘油市场还不能吸收生物柴油中过量的粗甘油。细菌菌株（例如梭菌属）可利用粗甘油，高产率生产丁醇。拟议项目将利用粗甘油，目前的废物流从生物柴油工业作为原料，生产生物丁醇，更高价值的燃料和平台化学品。

The goal of the proposed project is to develop an efficient biobutanol production process using bacterial fermentation and crude glycerol as feedstock generated as a low value by-product of the biodiesel industry. Biobased production of butanol from renewable feedstock is a promising and sustainable alternative to substitute petroleum based fuels and platform chemicals. There has been a resurgence of commercial interest in butanol from fermentation in the last decade (Butamax, Gevo, Cobalt, etc.) using sugar-based feedstocks. Meanwhile there is an abundantly available supply of crude glycerol as a byproduct of biodiesel production. The global production of biodiesel increased from 959 million liters in 2001 to 15,760 million liters in 2009, a compounded annual growth rate of 41.9%, generating 1 kg of glycerol for every 10 kg of biodiesel produced. To date the glycerol market cannot come close to absorbing the crude glycerol excess from biodiesel. Strains of bacteria (e.g. Clostridia sp.) can utilize crude glycerol and produce butanol at high yields. The proposed project will utilize crude glycerol, the current waste-stream from the biodiesel industry as a feedstock to produce biobutanol, a higher value fuel and platform chemical.