Multiplexed Immunoassay Platform to Quantify Cytokines in Biological Samples

滑铁卢大学需要一个高通量系统来评估炎症标志物（“细胞因子”），该系统能够提供对新医疗器械材料和药物的有效性和耐受性进行研究所需的再现性、可靠性、稳健性和准确性。目前，测量生物体液中细胞因子最受推崇和研究最多的高通量系统是一种相对较新的仪器- Meso Scale Discovery （MSD）扇区成像仪。在该系统上运行的免疫分析具有超低的检测限，范围大，并且需要最少的样品来检测细胞因子。该系统将为滑铁卢大学三个不同院系的4名教员提供服务，即视光、药剂学和系统设计工程。

The University of Waterloo requires a high-throughput system for evaluating markers of inflammation ('cytokines') that is able to provide the reproducibility, reliability, robustness, and accuracy required for conducting research on the efficacy and tolerability of new medical device materials and pharmaceuticals. Currently, the most well respected and researched high-throughput system for measuring cytokines in biological fluids is a relatively new instrument - Meso Scale Discovery (MSD) SECTOR Imager. The immunological assays that run on this system have ultra-low detection limits, a large range, and require minimal sample to detect cytokines. This system will serve 4 faculty members in three different Departments/Schools at the University of Waterloo, namely Optometry, Pharmacy and Systems Design Engineering.