Multiplexed Immunoassay Platform to Quantify Cytokines in Biological Samples

用于量化生物样品中细胞因子的多重免疫分析平台

• 批准号: 472311-2015
• 负责人: Jones, Lyndon
• 金额: $ 3.73万
• 依托单位: University of Waterloo
• 依托单位国家: 加拿大
• 项目类别: Research Tools and Instruments - Category 1 (<$150,000)
• 财政年份: 2014
• 资助国家: 加拿大
• 起止时间: 2014-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=564717
• 关键词: Multiplexed; Immunoassay; Platform; Quantify; Cytokines

The University of Waterloo requires a high-throughput system for evaluating markers of inflammation ('cytokines') that is able to provide the reproducibility, reliability, robustness, and accuracy required for conducting research on the efficacy and tolerability of new medical device materials and pharmaceuticals. Currently, the most well respected and researched high-throughput system for measuring cytokines in biological fluids is a relatively new instrument - Meso Scale Discovery (MSD) SECTOR Imager. The immunological assays that run on this system have ultra-low detection limits, a large range, and require minimal sample to detect cytokines. This system will serve 4 faculty members in three different Departments/Schools at the University of Waterloo, namely Optometry, Pharmacy and Systems Design Engineering.

滑铁卢大学需要一个高通量的系统来评估炎症标志物(细胞因子)，该系统能够提供进行新医疗器械材料和药物的有效性和耐受性研究所需的重复性、可靠性、稳健性和准确性。目前，最受推崇和研究的高通量生物体液细胞因子测量系统是一种相对较新的仪器-中尺度发现(MSD)扇形成像仪。在该系统上运行的免疫学检测具有超低检测限，范围大，需要最少的样本来检测细胞因子。该系统将为滑铁卢大学三个不同系/学院的4名教职员工提供服务，这三个系分别是验光学、药剂学和系统设计工程。