Functional surfaces for the disinfection and prevention of biofilm adhesion

用于消毒和防止生物膜粘附的功能表面

• 批准号: 484316-2015
• 负责人: Wilkinson, Kevin
• 金额: $ 1.82万
• 依托单位: Université de Montréal
• 依托单位国家: 加拿大
• 项目类别: Engage Grants Program
• 财政年份: 2015
• 资助国家: 加拿大
• 起止时间: 2015-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=584236
• 关键词: Functional; surfaces; disinfection; prevention; biofilm

Numerous disinfectants with different chemical structures can be used for the disinfection of surfaces. However, the adhesion of bacterial biofilms will modify surface properties and can greater reduce the efficiency of the disinfectants. The goal of this project is to work together with Avmor in order to develop chemicals with novel surface properties that can both prevent biofilm adhesion and improve disinfection efficiency. We will relate the physicochemical structure and properties of different functionalized surfaces to the production and growth of bacteria and bacterial biofilms. Our short-term objective will be to determine properties of several formulations of surface bound alkylated silanols, including their surface charge, size and morphology, as well as their ability to prevent the adhesion of bacterial biofilms.

具有不同化学结构的许多消毒剂可用于表面消毒。 然而，细菌生物膜的粘附将改变表面性质，并且可以更大地减少细菌的粘附。 消毒剂的功效。该项目的目标是与Avmor合作， 具有新型表面特性的化学品，既可防止生物膜粘附，又可改善消毒效果 效率我们将把不同功能化表面的物理化学结构和性质， 细菌和细菌生物膜的产生和生长。我们的短期目标是确定 表面结合的烷基化硅烷醇的几种制剂的性质，包括它们的表面电荷、尺寸和 形态，以及它们防止细菌生物膜粘附的能力。