Ultrasonic phantom materials for equipment calibration

用于设备校准的超声波体模材料

• 批准号: 490585-2015
• 负责人: Sinclair, Anthony
• 金额: $ 1.82万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Engage Grants Program
• 财政年份: 2015
• 资助国家: 加拿大
• 起止时间: 2015-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=586539
• 关键词: Ultrasonic; phantom; materials; equipment; calibration

Users of ultrasonic scanning systems for high frequency biomedical research require "phantoms" made of tissue-mimicking materials in order to calibrate the ultrasonic signals and understand the images acquired by the equipment. Without such phantoms, it is not practical to compare experimental results from different laboratories, or to transfer research findings to a clinical setting. Our objective in this project is to develop a new stable phantom material that has a similar response to ultrasound to that of human tissue at frequencies up to 50 MHz. Once this tissue-mimicking material has been developed, it can also be used by our industrial partner FujiFilmVisualSonics to assemble more complex phantoms that can be used for technician training or interpretation of ultrasonic images. The key challenge in this project is to attain appropriate levels of ultrasonic velocity, attenuation, and density to mimic human tissue - all within a single, stable material. By adjusting the amount of cross-linking of polymer chains during the manufacturing response, we intend to adjust the ultrasonic damping to bring it in line with almost any specified biomedical tissue. A process to embed thin tungsten wire filaments and nylon fibers in straight lines inside the phantom material for equipment calibration purposes is also being developed; these targets will provide a suitable calibration test for equipment to confirm that its sensitivity and resolution meet required specifications. The VisualSonics equipment could then be used with confidence to characterize any anomalies in real tissue samples, and allow research findings to be accurately evaluated.

用于高频生物医学研究的超声波扫描系统的用户需要由模拟组织材料制成的“幽灵”，以便校准超声波信号并理解设备获得的图像。没有这样的幻影，比较不同实验室的实验结果或将研究成果转移到临床环境是不切实际的。我们在这个项目中的目标是开发一种新的稳定的幻体材料，在高达50兆赫的频率下，它对超声波的反应与人体组织的反应相似。一旦这种组织模拟材料被开发出来，它也可以被我们的工业合作伙伴FujiFilmVisualSonics用来组装更复杂的幻影，可用于技术人员培训或解释超声波图像。