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Mobility, organization and signalling of immune cell surface receptors

Mobility, organization and signalling of immune cell surface receptors
免疫细胞表面受体的移动性、组织和信号传导
批准号：
RGPIN-2015-04611
负责人：
Coombs, Daniel
金额：
$3.79万
依托单位：
University of British Columbia
依托单位国家：
加拿大
项目类别：
Discovery Grants Program - Individual
财政年份：
2015
资助国家：
加拿大
项目状态：
已结题
起止时间：
2015-01-01 至 2016-12-31
来源：
https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=589905
关键词：
Mobilityorganizationsignallingimmunecell

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中文摘要
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英文摘要
B cells are an essential part of the adaptive immune response. In vivo, B cells can become activated (leading to proliferation and secretion of antibodies that bind to and neutralize invading pathogens) after binding specific antigens with their B cell receptors (BCR). B cell surface receptors are known to spatially organize themselves during antigenic signal detection. Therefore, in order to obtain a proper understanding of B cell activation, we need to study the motion of surface molecules such as BCR and relate their motion to the biochemical reactions within the cell that lead to cell activation.
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Super-resolution imaging, single cell analysis, and modelling approaches applied to the study of immune cell signaling and behaviour
  • 批准号：
    RGPIN-2020-04820
  • 项目类别：
    Discovery Grants Program - Individual
  • 资助金额：
    $5.03万
  • 财政年份：
    2022
  • 负责人：
    Coombs, Daniel
  • 依托单位：
    University of British Columbia
Super-resolution imaging, single cell analysis, and modelling approaches applied to the study of immune cell signaling and behaviour
  • 批准号：
    RGPIN-2020-04820
  • 项目类别：
    Discovery Grants Program - Individual
  • 资助金额：
    $5.03万
  • 财政年份：
    2021
  • 负责人：
    Coombs, Daniel
  • 依托单位：
    University of British Columbia
Super-resolution imaging, single cell analysis, and modelling approaches applied to the study of immune cell signaling and behaviour
  • 批准号：
    RGPIN-2020-04820
  • 项目类别：
    Discovery Grants Program - Individual
  • 资助金额：
    $5.03万
  • 财政年份：
    2020
  • 负责人：
    Coombs, Daniel
  • 依托单位：
    University of British Columbia
Mobility, organization and signalling of immune cell surface receptors
  • 批准号：
    RGPIN-2015-04611
  • 项目类别：
    Discovery Grants Program - Individual
  • 资助金额：
    $3.79万
  • 财政年份：
    2019
  • 负责人：
    Coombs, Daniel
  • 依托单位：
    University of British Columbia
国内基金
海外基金
功能有机配体新颖设计与有机金属超分子导向组装
  • 批准号：
    20772152
  • 项目类别：
    面上项目
  • 资助金额：
    28.0万元
  • 批准年份：
    2007
  • 负责人：
    于澍燕
  • 依托单位：
    中国人民大学