Spatial organization of T cell signalling
Spatial organization of T cell signalling
批准号:
nhmrc : GNT1059278
负责人:
Prof Katharina Gaus
金额:
$60.14万
依托单位国家:
澳大利亚
项目类别:
Research Fellowships
财政年份:
2014
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2014-01-01 至 --
中文摘要
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英文摘要
The regulation to early T cell signalling is a critical step in immune responses. Superimposed onto the biochemical pathways is a spatial organization that defines the immunological synapse. My research aims to map the principles of the spatial organization on the molecular scale to identify how lipids could unbalance the dynamic signalling equilibrium, for example in obese patients. To achieve this goal, my research group has developed single molecule microscopy approaches.
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T cell receptor (TCR) singalling efficiency
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批准号:nhmrc : GNT1155162
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项目类别:Research Fellowships
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资助金额:$64.92万
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财政年份:2019
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负责人:Prof Katharina Gaus
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依托单位:
Confocal and single molecule microscopes for systems microscopy
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批准号:LE180100157
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项目类别:Linkage Infrastructure, Equipment and Facilities
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资助金额:$40.01万
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财政年份:2018
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负责人:Prof Katharina Gaus
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依托单位:
DNA nanotechnology for controlled antigen presentation to T cells
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批准号:DP170102727
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项目类别:Discovery Projects
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资助金额:$33.97万
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财政年份:2017
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负责人:Prof Katharina Gaus
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依托单位:
Statistical analyses for spatial organisation in T cell signalling networks
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批准号:DP170103599
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项目类别:Discovery Projects
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资助金额:$27.9万
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财政年份:2017
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负责人:Prof Katharina Gaus
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依托单位:
Modulating T cell responses with novel Lck activating compounds
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批准号:LP160100979
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项目类别:Linkage Projects
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资助金额:$23.3万
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财政年份:2016
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负责人:Prof Katharina Gaus
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依托单位:
Single molecule imaging laboratory
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批准号:LE150100163
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项目类别:Linkage Infrastructure, Equipment and Facilities
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资助金额:$37.34万
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财政年份:2015
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负责人:Prof Katharina Gaus
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依托单位:
Connecting the dots: Image analysis for single molecule localisation microscopy
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批准号:LP140100967
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项目类别:Linkage Projects
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资助金额:$27.23万
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财政年份:2015
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负责人:Prof Katharina Gaus
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依托单位:
Spatial organization of T cell signalling
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批准号:nhmrc : 1059278
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项目类别:Research Fellowships
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资助金额:$42.08万
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财政年份:2014
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负责人:Prof Katharina Gaus
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依托单位:
Nano-scale organisation of cellular adhesions
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批准号:DP130100269
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项目类别:Discovery Projects
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资助金额:$33.04万
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财政年份:2013
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负责人:Prof Katharina Gaus
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依托单位:
Molecular interactions in cell membranes
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批准号:LP110100390
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项目类别:Linkage Projects
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资助金额:$30.27万
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财政年份:2012
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负责人:Prof Katharina Gaus
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依托单位:
Life at the nanometre scale: imaging immunological synapses with a novel super-resolution fluorescence microscope
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批准号:LP100200021
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项目类别:Linkage Projects
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资助金额:$30.06万
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财政年份:2011
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负责人:Prof Katharina Gaus
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依托单位:
Molecular microscopy: protein and membrane dynamics in resting and activated T cells
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批准号:DP1095468
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项目类别:Discovery Projects
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资助金额:$22.99万
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财政年份:2010
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负责人:Prof Katharina Gaus
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依托单位:
Super-resolution fluorescence microscopy
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批准号:LE100100089
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项目类别:Linkage Infrastructure, Equipment and Facilities
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资助金额:$46.68万
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财政年份:2010
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负责人:Prof Katharina Gaus
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依托单位:
Uncoupled Research Fellowship
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批准号:nhmrc : 568716
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项目类别:NHMRC Research Fellowships
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资助金额:$38.72万
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财政年份:2009
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负责人:Prof Katharina Gaus
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依托单位:
High-resolution imaging of live cells and tissue
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批准号:LE0882855
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项目类别:Linkage Infrastructure, Equipment and Facilities
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资助金额:$60.01万
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财政年份:2008
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负责人:Prof Katharina Gaus
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依托单位:
Molecular mechanisms in cholesterol export.
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批准号:nhmrc : 455301
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项目类别:NHMRC Project Grants
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资助金额:$34.41万
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财政年份:2007
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负责人:Prof Katharina Gaus
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依托单位:
Lipid raft and cyotoskeleton organization: How membrane domains give cells direction
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批准号:DP0556554
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项目类别:Discovery Projects
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资助金额:$17.56万
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财政年份:2005
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负责人:Prof Katharina Gaus
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依托单位:
Lipid raft organisation in mammalian cells
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批准号:nhmrc : 350986
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项目类别:Career Development Fellowships
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资助金额:$23.95万
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财政年份:2005
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负责人:Prof Katharina Gaus
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依托单位:
Cholesterol-dependent control of plasma membrane lipid rafts
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批准号:DP0212068
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项目类别:Discovery Projects
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资助金额:$16.13万
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财政年份:2002
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负责人:Prof Katharina Gaus
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依托单位:
国内基金
海外基金
功能有机配体新颖设计与有机金属超分子导向组装
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批准号:20772152
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项目类别:面上项目
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资助金额:28.0万元
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批准年份:2007
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负责人:于澍燕
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依托单位: