Lattice materials with graded mechanical properties for the development of a novel hip-replacement implant

用于开发新型髋关节置换植入物的具有分级机械性能的晶格材料

• 批准号: 312544-2012
• 负责人: Pasini, Damiano
• 金额: $ 2.77万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2016
• 资助国家: 加拿大
• 起止时间: 2016-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=595110
• 关键词: Lattice; materials; graded; mechanical; properties

On average, hip-replacements have a life span of 15-20 years, after which revision surgery is necessary. A revision surgery is undesirable, problematic and less successful than a primary replacement. Problematic is the inadequate capacity of current implants to preserve the quality of the host bone, which thus cannot sufficiently secure the revision implant into position. The aim of this research program is to develop a novel material microstructure for a total hip arthroplasty implant which can last longer, maintain the quality of the host bone, and provide a stable implant fixation. The proposed material is a titanium alloy, Ti-6AL-4V, lattice; its groundbreaking hallmark lies in the controlled gradients of material properties which are designed to match the local properties of the bone and provide unprecedented elastic and strength properties as well as superior fatigue, damage and wear resistance. The new implant will enhance the treatment of patients requiring primary and revision hip replacement, lower the need of revision surgery and the related health care cost; in case of revision surgeries, it will increase its success rate.

平均而言，髋关节置换的寿命为15 - 20年，之后进行了修订手术。与主要替代者相比，修订手术是不希望的，有问题的，而且成功的效果较小。有问题的是，当前植入物保持宿主骨骼质量的能力不足，因此无法充分将修订植入物置于适当的位置。该研究计划的目的是为总髋关节置换术植入物开发一种新型的材料微观结构，该植入物可以持续更长的时间，维持宿主骨骼的质量并提供稳定的植入物固定。提出的材料是钛合金，Ti-6al-4V，晶格；它的开创性标志在于材料特性的受控梯度，旨在与骨骼的局部特性相匹配，并提供前所未有的弹性和强度特性以及出色的疲劳，损坏和耐磨性。新的植入物将增强需要髋关节置换髋关节的患者的治疗，降低修订手术的需求以及相关的医疗保健成本；如果进行修订手术，它将提高其成功率。