Hypertensive heart disease is regulated by distinct cardiac macrophage lineages controlled by the Renin-Angiotensin System

高血压性心脏病受到肾素-血管紧张素系统控制的不同心脏巨噬细胞谱系的调节

• 批准号: 344521
• 负责人: Epelman Slava
• 金额: $ 63.21万
• 依托单位: University Health Network (Toronto)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2016
• 资助国家: 加拿大
• 起止时间: 2016-03-01 至 2021-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=344521&lang=en
• 关键词: Angiotensin; Cardiac; Fibrosis; Hypertension; Macrophage

High blood pressure causes hypertensive heart disease, which is one of the 10 leading causes of death worldwide despite significant investment in medical therapies. In animal studies, our group has made two important new findings that may help explain how

高血压导致高血压性心脏病，这是世界范围内十大死亡原因之一，尽管在医学治疗方面投入了大量资金。在动物研究中，我们的团队有两个重要的新发现，可能有助于解释