Differential type I interferon responses drive sex-specific vulnerability to viral myocarditis
I 型干扰素反应差异导致性别特异性对病毒性心肌炎的脆弱性
基本信息
- 批准号:487141
- 负责人:
- 金额:$ 7.29万
- 依托单位:
- 依托单位国家:加拿大
- 项目类别:Operating Grants
- 财政年份:2023
- 资助国家:加拿大
- 起止时间:2023-04-01 至 2024-04-01
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Viral myocarditis is an important contributor to the development of heart failure - a devastating diagnosis with a 5-year mortality rate of 74%. Importantly, there is compelling evidence that the clinical impact of viral myocarditis and viral-induced card
病毒性心肌炎是心力衰竭发展的一个重要因素--这是一种毁灭性的诊断,5年死亡率为74%。重要的是,有令人信服的证据表明,病毒性心肌炎和病毒诱发的卡介苗的临床影响
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Epelman Slava其他文献
Epelman Slava的其他文献
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{{ truncateString('Epelman Slava', 18)}}的其他基金
Differential type I interferon responses drive sex-specific vulnerability to viral myocarditis
I 型干扰素反应差异导致性别特异性对病毒性心肌炎的脆弱性
- 批准号:
488319 - 财政年份:2023
- 资助金额:
$ 7.29万 - 项目类别:
Operating Grants
Cardioprotection during hypertensive heart disease is mediated through anti-viral cytokine pathways
高血压心脏病期间的心脏保护是通过抗病毒细胞因子途径介导的
- 批准号:
461883 - 财政年份:2022
- 资助金额:
$ 7.29万 - 项目类别:
Operating Grants
An unexpected role for type I Interferon underlies cardiac adaptation to stress and prevents heart failure
I 型干扰素在心脏适应压力和预防心力衰竭方面发挥着意想不到的作用
- 批准号:
444878 - 财政年份:2021
- 资助金额:
$ 7.29万 - 项目类别:
Operating Grants
Cerebrovascular-immune interfaces: searching for an immune signature coupling hypertension to cognitive dysfunction (ImmuneHyperCog).
脑血管-免疫界面:寻找将高血压与认知功能障碍耦合的免疫特征(ImmuneHyperCog)。
- 批准号:
425187 - 财政年份:2020
- 资助金额:
$ 7.29万 - 项目类别:
Operating Grants
Fate, function and high-dimensional analyses of monocyte-derived macrophages in viral cardiomyopathy
病毒性心肌病中单核细胞源性巨噬细胞的命运、功能和高维分析
- 批准号:
408856 - 财政年份:2019
- 资助金额:
$ 7.29万 - 项目类别:
Operating Grants
Gut-brain interactions modulate immune response in hypertensive heart disease
肠脑相互作用调节高血压心脏病的免疫反应
- 批准号:
405902 - 财政年份:2019
- 资助金额:
$ 7.29万 - 项目类别:
Operating Grants
NEural MOdulation of IMMUNE system to shape cardiac remodeling to chronic Arterial hypertension and counteract Heart Failure
免疫系统的神经调节塑造慢性动脉高血压的心脏重塑并对抗心力衰竭
- 批准号:
392721 - 财政年份:2018
- 资助金额:
$ 7.29万 - 项目类别:
Operating Grants
Hypertensive heart disease is regulated by distinct cardiac macrophage lineages controlled by the Renin-Angiotensin System
高血压性心脏病受到肾素-血管紧张素系统控制的不同心脏巨噬细胞谱系的调节
- 批准号:
344521 - 财政年份:2016
- 资助金额:
$ 7.29万 - 项目类别:
Operating Grants
Primitive cardiac macrophages and their reparative role following ischemic injury
原始心脏巨噬细胞及其缺血性损伤后的修复作用
- 批准号:
344704 - 财政年份:2016
- 资助金额:
$ 7.29万 - 项目类别:
Operating Grants
Role of Embryonic-Derived Cardiac Macrophages in Tissue Repair
胚胎来源的心脏巨噬细胞在组织修复中的作用
- 批准号:
340666 - 财政年份:2015
- 资助金额:
$ 7.29万 - 项目类别:
Salary Programs
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