Fate, function and high-dimensional analyses of monocyte-derived macrophages in viral cardiomyopathy

病毒性心肌病中单核细胞源性巨噬细胞的命运、功能和高维分析

• 批准号: 408856
• 负责人: Epelman Slava
• 金额: $ 66.32万
• 依托单位: University Health Network (Toronto)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2019
• 资助国家: 加拿大
• 起止时间: 2019-09-01 至 2024-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=408856&lang=en
• 关键词: Fate Mapping; Macrophages; Monocytes; Mouse; Myocarditis; Virus

We have found that the heart contains multiple novel macrophage / dendritic cell subsets, which have never been discovered before. For last 50 years, scientists have always thought immune cells in the body are produced from stem cells in the bone marrow.

我们发现心脏含有多个新的巨噬细胞/树突状细胞亚群，这是以前从未发现的。在过去的50年里，科学家们一直认为体内的免疫细胞是由骨髓中的干细胞产生的。