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Fate, function and high-dimensional analyses of monocyte-derived macrophages in viral cardiomyopathy

Fate, function and high-dimensional analyses of monocyte-derived macrophages in viral cardiomyopathy
病毒性心肌病中单核细胞源性巨噬细胞的命运、功能和高维分析
批准号:
408856
负责人:
Epelman Slava
金额:
$66.32万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2019
资助国家:
加拿大
项目状态:
已结题
起止时间:
2019-09-01 至 2024-09-01

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中文摘要
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英文摘要
We have found that the heart contains multiple novel macrophage / dendritic cell subsets, which have never been discovered before. For last 50 years, scientists have always thought immune cells in the body are produced from stem cells in the bone marrow.
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会议论文
Differential type I interferon responses drive sex-specific vulnerability to viral myocarditis
  • 批准号:
    487141
  • 项目类别:
    Operating Grants
  • 资助金额:
    $7.29万
  • 财政年份:
    2023
  • 负责人:
    Epelman Slava
  • 依托单位:
Differential type I interferon responses drive sex-specific vulnerability to viral myocarditis
  • 批准号:
    488319
  • 项目类别:
    Operating Grants
  • 资助金额:
    $66.32万
  • 财政年份:
    2023
  • 负责人:
    Epelman Slava
  • 依托单位:
Cardioprotection during hypertensive heart disease is mediated through anti-viral cytokine pathways
  • 批准号:
    461883
  • 项目类别:
    Operating Grants
  • 资助金额:
    $66.6万
  • 财政年份:
    2022
  • 负责人:
    Epelman Slava
  • 依托单位:
An unexpected role for type I Interferon underlies cardiac adaptation to stress and prevents heart failure
  • 批准号:
    444878
  • 项目类别:
    Operating Grants
  • 资助金额:
    $66.32万
  • 财政年份:
    2021
  • 负责人:
    Epelman Slava
  • 依托单位:
国内基金
海外基金
支链氨基酸代谢紊乱调控“Adipocytes - Macrophages Crosstalk”诱发2型糖尿病脂肪组织功能和结构障碍的作用及机制