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Differential type I interferon responses drive sex-specific vulnerability to viral myocarditis

Differential type I interferon responses drive sex-specific vulnerability to viral myocarditis
I 型干扰素反应差异导致性别特异性对病毒性心肌炎的脆弱性
批准号:
488319
负责人:
Epelman Slava
金额:
$66.32万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2023
资助国家:
加拿大
项目状态:
未结题
起止时间:
2023-09-01 至 2028-09-01

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英文摘要
Viral myocarditis is an important contributor to the development of heart failure - a devastating diagnosis with a 5-year mortality rate of 74%. Importantly, there is compelling evidence that the clinical impact of viral myocarditis and viral-induced card
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Differential type I interferon responses drive sex-specific vulnerability to viral myocarditis
  • 批准号:
    487141
  • 项目类别:
    Operating Grants
  • 资助金额:
    $7.29万
  • 财政年份:
    2023
  • 负责人:
    Epelman Slava
  • 依托单位:
Cardioprotection during hypertensive heart disease is mediated through anti-viral cytokine pathways
  • 批准号:
    461883
  • 项目类别:
    Operating Grants
  • 资助金额:
    $66.6万
  • 财政年份:
    2022
  • 负责人:
    Epelman Slava
  • 依托单位:
An unexpected role for type I Interferon underlies cardiac adaptation to stress and prevents heart failure
  • 批准号:
    444878
  • 项目类别:
    Operating Grants
  • 资助金额:
    $66.32万
  • 财政年份:
    2021
  • 负责人:
    Epelman Slava
  • 依托单位:
Cerebrovascular-immune interfaces: searching for an immune signature coupling hypertension to cognitive dysfunction (ImmuneHyperCog).
  • 批准号:
    425187
  • 项目类别:
    Operating Grants
  • 资助金额:
    $21.86万
  • 财政年份:
    2020
  • 负责人:
    Epelman Slava
  • 依托单位:
海外基金