3D bioprinted cell seeded POEGMA hydrogels as tissue mimics

3D 生物打印细胞接种 POEGMA 水凝胶作为组织模拟物

• 批准号: 506209-2016
• 负责人: Wylie, Ryan
• 金额: $ 1.82万
• 依托单位: McMaster University
• 依托单位国家: 加拿大
• 项目类别: Engage Grants Program
• 财政年份: 2016
• 资助国家: 加拿大
• 起止时间: 2016-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=610144
• 关键词: 3D; bioprinted; cell; seeded; POEGMA

The development of tissue mimics from non-animal sources will greatly increase research productivity in biomedical sciences. Specifically, tissue mimics are being developed to increase drug screening efficiency, to better understand complex mechanisms of disease, and to create implantable tissues to replace diseased or worn-out organs. Therefore, better tissue mimics will lead to more pharmaceutical drugs candidates, new treatments for complex diseases such as cancer and non-human sources of donor organs. Currently, tissue mimics are difficult and time-consuming to synthesize, and lack the chemical and mechanical complexity of

非动物来源的组织模拟物的开发将极大地提高生物医学科学的研究生产率。具体地说，正在开发组织模拟物，以提高药物筛选效率，更好地了解复杂的疾病机制，并创造可移植组织来取代患病或磨损的器官。因此，更好的组织模拟将导致更多的候选药物、癌症等复杂疾病的新疗法以及非人类来源的捐赠器官。目前，组织模拟物的合成既困难又耗时，而且缺乏