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Manufacturing methods for mucoadhesive micelles

Manufacturing methods for mucoadhesive micelles
粘膜粘附胶束的制造方法
批准号:
508631-2017
负责人:
Sheardown, Heather
金额:
$9.11万
依托单位:
依托单位国家:
加拿大
项目类别:
Idea to Innovation
财政年份:
2017
资助国家:
加拿大
项目状态:
已结题
起止时间:
2017-01-01 至 2018-12-31

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英文摘要
A novel mucoadhesive micelle has been developed which can be formulated with a therapeutic for drug delivery to the eye. Testing of micelles synthesized using RAFT polymerization containing cyclosporine A has demonstrated the efficacy of the formulation. Details can be found at: http://www.2020optimeyes.ca/Documents/I2I.pdf The proposed project will focus on creating the micelles using the more industrially-friendly and scalable free radical polymerization method, and exploring the potential manufacturing strategies of these drug loaded compounds. This will allow industrial partners to assess the licensing potential of these materials using a synthesis method consistent with their standard practices.
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