Studies on the relationship between lower-cost low protein complexity feed and genetics with health and growth performance in pigs

低成本低蛋白复杂度饲料和遗传与猪健康和生长性能关系的研究

基本信息

  • 批准号:
    488429-2015
  • 负责人:
  • 金额:
    $ 2.92万
  • 依托单位:
  • 依托单位国家:
    加拿大
  • 项目类别:
    Collaborative Research and Development Grants
  • 财政年份:
    2017
  • 资助国家:
    加拿大
  • 起止时间:
    2017-01-01 至 2018-12-31
  • 项目状态:
    已结题

项目摘要

Reduction of production cost via alternate feeding strategies is a research priority of the swine industry. Our recent study showed lower cost reduced animal-protein (low protein complexity) diets can be fed to nursery pigs without negative impacts on performance up to market weight as long as pigs do not become diseased. We have also identified pig genotypes associated with improved growth rate and infectious disease resistance, but the cumulative impact of feed quality, genotype, and health on pig growth performance under commercial farming conditions is unclear. This study will examine the application of lower-cost diets, and investigate whether pigs with improved genetic resistance to infectious diseases perform better under these diets/conditions. Pigs on commercial farms will be fed either a lower cost reduced animal low complexity protein diet or conventional diet during 2 different seasons. Pigs will be weighed multiple times and monitored for disease; sick pigs will be necropsied to diagnose disease etiologies. Blood, feces and nasal swabs will be tested for the presence of swine pathogens, and serum immune/growth biomarkers will be analyzed, and pigs genotyped for defects in innate disease resistance genes. At slaughter a subset of pigs will be evaluated for carcass dressing percentage and lean yield to determine the impact of the diets on carcass quality. We will determine the feasibility of using alternative lower cost reduced animal protein diets in a commercial setting. We will also identify parameters that impact growth performance under commercial conditions and resistance to infectious agents during the various stages of growth and relate these to productivity up to market weight and carcass quality, to help maximize the economic benefits of this alternative less expensive nursery diet. This study will provide valuable knowledge usable by producers and feed and genetics companies towards the use of less expensive feeds as well as selection of more robust pig genotypes and/or pigs with superior growth performance. The result for Canadians will be a stronger swine industry with improved animal welfare, safer pork for consumption, and reduced use of antimicrobials thus helping in the war on antimicrobial resistance.
通过替代饲养策略降低生产成本是养猪业的研究重点。我们最近的研究表明,只要猪不生病,低成本低动物蛋白(低蛋白质复杂性)的饮食可以喂给保育猪,而不会对市场体重的性能产生负面影响。我们还确定了与提高生长速度和传染病抗性相关的猪基因型,但在商业化养殖条件下,饲料质量、基因型和健康对猪生长性能的累积影响尚不清楚。本研究将研究低成本饲料的应用,并调查在这些饲料/条件下,对传染病具有改进的遗传抗性的猪是否表现更好。在2个不同的季节,商业农场的猪将被喂食成本较低的动物低复杂性蛋白质饲料或常规饲料。将对猪进行多次称重并监测疾病;将对患病猪进行尸检以诊断疾病病因。将检测血液、粪便和鼻拭子中是否存在猪病原体,分析血清免疫/生长生物标志物,并对猪进行先天性抗病基因缺陷基因分型。屠宰时,将对一部分猪的胴体屠宰率和瘦肉产量进行评价,以确定饲料对胴体质量的影响。我们将确定在商业环境中使用替代性低成本低动物蛋白饮食的可行性。我们还将确定在商业条件下影响生长性能的参数,以及在生长的各个阶段对感染性病原体的抵抗力,并将这些参数与生产力、市场重量和胴体质量联系起来,以帮助最大限度地提高这种替代性较便宜的保育饲料的经济效益。本研究将为生产商、饲料和遗传公司提供有价值的知识,以使用更便宜的饲料,以及选择更健壮的猪基因型和/或具有上级生长性能的猪。对加拿大人来说,结果将是一个更强大的养猪业,改善动物福利,更安全的猪肉消费,减少抗菌素的使用,从而有助于对抗抗菌素耐药性。

项目成果

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专著数量(0)
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Lillie, Brandon其他文献

Two DNA vaccines protect against severe disease and pathology due to SARS-CoV-2 in Syrian hamsters.
  • DOI:
    10.1038/s41541-022-00461-5
  • 发表时间:
    2022-04-26
  • 期刊:
  • 影响因子:
    9.2
  • 作者:
    Babuadze, George Giorgi;Fausther-Bovendo, Hugues;deLaVega, Marc-Antoine;Lillie, Brandon;Naghibosadat, Maedeh;Shahhosseini, Nariman;Joyce, Michael A.;Saffran, Holly A.;Lorne Tyrrell, D.;Falzarano, Darryl;Senthilkumaran, Chandrika;Christie-Holmes, Natasha;Ahn, Steven;Gray-Owen, Scott D.;Banerjee, Arinjay;Mubareka, Samira;Mossman, Karen;Dupont, Chanel;Pedersen, Jannie;Lafrance, Mark-Alexandre;Kobinger, Gary P.;Kozak, Robert
  • 通讯作者:
    Kozak, Robert

Lillie, Brandon的其他文献

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{{ truncateString('Lillie, Brandon', 18)}}的其他基金

Comparative innate immunity in domestic large animals
家养大型动物的先天免疫比较
  • 批准号:
    418356-2012
  • 财政年份:
    2019
  • 资助金额:
    $ 2.92万
  • 项目类别:
    Discovery Grants Program - Individual
Comparative innate immunity in domestic large animals
家养大型动物的先天免疫比较
  • 批准号:
    418356-2012
  • 财政年份:
    2018
  • 资助金额:
    $ 2.92万
  • 项目类别:
    Discovery Grants Program - Individual
Studies on the relationship between lower-cost low protein complexity feed and genetics with health and growth performance in pigs
低成本低蛋白复杂度饲料和遗传与猪健康和生长性能关系的研究
  • 批准号:
    488429-2015
  • 财政年份:
    2018
  • 资助金额:
    $ 2.92万
  • 项目类别:
    Collaborative Research and Development Grants
Studies on the relationship between lower-cost low protein complexity feed and genetics with health and growth performance in pigs
低成本低蛋白复杂度饲料和遗传与猪健康和生长性能关系的研究
  • 批准号:
    488429-2015
  • 财政年份:
    2016
  • 资助金额:
    $ 2.92万
  • 项目类别:
    Collaborative Research and Development Grants
Comparative innate immunity in domestic large animals
家养大型动物的先天免疫比较
  • 批准号:
    418356-2012
  • 财政年份:
    2015
  • 资助金额:
    $ 2.92万
  • 项目类别:
    Discovery Grants Program - Individual
Comparative innate immunity in domestic large animals
家养大型动物的先天免疫比较
  • 批准号:
    418356-2012
  • 财政年份:
    2014
  • 资助金额:
    $ 2.92万
  • 项目类别:
    Discovery Grants Program - Individual
Comparative innate immunity in domestic large animals
家养大型动物的先天免疫比较
  • 批准号:
    418356-2012
  • 财政年份:
    2013
  • 资助金额:
    $ 2.92万
  • 项目类别:
    Discovery Grants Program - Individual
Comparative innate immunity in domestic large animals
家养大型动物的先天免疫比较
  • 批准号:
    418356-2012
  • 财政年份:
    2012
  • 资助金额:
    $ 2.92万
  • 项目类别:
    Discovery Grants Program - Individual
Genome-wide identification of genetic defects in innate disease resistance genes of swine
猪先天抗病基因遗传缺陷的全基因组鉴定
  • 批准号:
    402509-2010
  • 财政年份:
    2012
  • 资助金额:
    $ 2.92万
  • 项目类别:
    Collaborative Research and Development Grants
Genome-wide identification of genetic defects in innate disease resistance genes of swine
猪先天抗病基因遗传缺陷的全基因组鉴定
  • 批准号:
    402509-2010
  • 财政年份:
    2011
  • 资助金额:
    $ 2.92万
  • 项目类别:
    Collaborative Research and Development Grants

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