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Biophysical properties and regulation of KCNQ1 and KCNE(x) ion channel complexes.

Biophysical properties and regulation of KCNQ1 and KCNE(x) ion channel complexes.
KCNQ1 和 KCNE(x) 离子通道复合物的生物物理特性和调节。
批准号:
370760
负责人:
Fedida David
金额:
$45.7万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2017
资助国家:
加拿大
项目状态:
已结题
起止时间:
2017-09-01 至 2022-09-01

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中文摘要
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英文摘要
In this study we will examine a complex protein that is able to conduct potassium and has a vital role in maintaining the normal resting activity of excitable tissues. This protein is made up of two or three subunits which greatly affect its behavior whe
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Mechanisms of potassium channel activator action on Kv7.1 ion channel complexes.
  • 批准号:
    433343
  • 项目类别:
    Operating Grants
  • 资助金额:
    $70.78万
  • 财政年份:
    2020
  • 负责人:
    Fedida David
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Novel 3D bioprinted human cardiac tissue models for drug safety and efficacy testing.
  • 批准号:
    376028
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    Operating Grants
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    $27.81万
  • 财政年份:
    2017
  • 负责人:
    Fedida David
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Regulation of the voltage-activated potassium channel, IKs, by its accessory subunits, studied using unnatural amino acid mutagenesis and mass spectrometry.
  • 批准号:
    313961
  • 项目类别:
    Operating Grants
  • 资助金额:
    $7.29万
  • 财政年份:
    2014
  • 负责人:
    Fedida David
  • 依托单位:
Discovery & Development of Novel Small Molecule Inhibitors of Viroporin Proteins for the Treatment of Acute & Chronic Viral Infections.
  • 批准号:
    255430
  • 项目类别:
    Operating Grants
  • 资助金额:
    $42.0万
  • 财政年份:
    2012
  • 负责人:
    Fedida David
  • 依托单位:
海外基金