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Novel 3D bioprinted human cardiac tissue models for drug safety and efficacy testing.

Novel 3D bioprinted human cardiac tissue models for drug safety and efficacy testing.
用于药物安全性和功效测试的新型 3D 生物打印人体心脏组织模型。
批准号:
376028
负责人:
Fedida David
金额:
$27.81万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2017
资助国家:
加拿大
项目状态:
已结题
起止时间:
2017-11-01 至 2020-11-01

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中文摘要
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英文摘要
During human clinical trials, a large percentage of candidate drugs fail because they are unsafe or ineffective. Even when pre-clinical cell and animal studies seem positive, problems occur because tests done with drugs on these models are often not predi
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Mechanisms of potassium channel activator action on Kv7.1 ion channel complexes.
  • 批准号:
    433343
  • 项目类别:
    Operating Grants
  • 资助金额:
    $70.78万
  • 财政年份:
    2020
  • 负责人:
    Fedida David
  • 依托单位:
Biophysical properties and regulation of KCNQ1 and KCNE(x) ion channel complexes.
  • 批准号:
    370760
  • 项目类别:
    Operating Grants
  • 资助金额:
    $45.7万
  • 财政年份:
    2017
  • 负责人:
    Fedida David
  • 依托单位:
Regulation of the voltage-activated potassium channel, IKs, by its accessory subunits, studied using unnatural amino acid mutagenesis and mass spectrometry.
  • 批准号:
    313961
  • 项目类别:
    Operating Grants
  • 资助金额:
    $7.29万
  • 财政年份:
    2014
  • 负责人:
    Fedida David
  • 依托单位:
Discovery & Development of Novel Small Molecule Inhibitors of Viroporin Proteins for the Treatment of Acute & Chronic Viral Infections.
  • 批准号:
    255430
  • 项目类别:
    Operating Grants
  • 资助金额:
    $42.0万
  • 财政年份:
    2012
  • 负责人:
    Fedida David
  • 依托单位:
海外基金