An integrative approach to stress physiology in fish

我的研究计划的长期目标是了解鱼的应激生理学。包括鱼类在内的大多数动物经常面临威胁其动态平衡的环境挑战。启动一系列协调的行为、神经内分泌和细胞事件，统称为应激反应，使动物能够对这些应激源做出反应。尽管压力反应对个体和群体的生存和健康非常重要，但我们对压力反应如何调节以及如何与其他生理系统整合的了解仍然有限，特别是在慢性压力期间。此外，随着早期生活逆境和压力在塑造下一代压力生理和行为方面的代际影响的证据的积累，压力生理学领域正变得更加复杂。

The long-term objective of my research program is to understand the physiology of stress in fish. Most animals, including fish, regularly face environmental challenges that threaten their homeostasis. The initiation of a coordinated suite of behavioural, neuroendocrine and cellular events, collectively termed a stress response, allows the animal to respond to such stressors. Despite the importance of stress responses to the survival and fitness of individuals and populations, our knowledge of how they are regulated and integrated with other physiological systems remains limited, particularly during chronic stress. Moreover, the field of stress physiology is becoming more complex as evidence accrues for early life adversity and intergenerational effects of stress in shaping the stress physiology and behaviour of the next generation.