Supramolecular-based Fluorescent Sensors and Surfactants

超分子化学，或“分子之外的化学”，涉及由两个或多个分子组成的结构，这些分子通过弱引力而不是化学键结合在一起。超分子系统的一个简单例子是主-客包合复合物，其中客分子被包含在一个更大的笼状有机宿主分子的腔中（就像桶里的球）。最常见的宿主分子家族是环糊精（CDs），这是葡萄糖的环状形式，在水中呈桶状，并在其内部腔内强烈结合客体分子。在我的研究小组之前成功的基于荧光的主客体包涵体系基本特性研究的基础上，本提案支持的变革性研究涉及超分子系统在两个重要领域的新应用：1)

Supramolecular chemistry, or "chemistry beyond the molecule", involves structures consisting of two or more molecules held together by weak forces of attraction as opposed to chemical bonds. A simple example of a supramolecular system is a host-guest inclusion complex, in which a guest molecule becomes included within the cavity of a larger, cage-like organic host molecule (like a ball in a bucket). The most common family of host molecules are the cyclodextrins (CDs), cyclic forms of glucose sugar that take on a bucket-like shape in water, and strongly bind guest molecules inside their internal cavities. Building upon the previous success in my research group involving fluorescence-based investigations of the fundamental properties of host-guest inclusion systems, the transformative research to be supported by this proposal involves the novel application of such supramolecular systems in two important areas: 1)