Supramolecular-based Fluorescent Sensors and Surfactants

超分子荧光传感器和表面活性剂

• 批准号: RGPIN-2016-04905
• 负责人: Wagner, Brian
• 金额: $ 1.82万
• 依托单位: University of Prince Edward Island
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=632554
• 关键词: Supramolecular; based; Fluorescent; Sensors; Surfactants

Supramolecular chemistry, or "chemistry beyond the molecule", involves structures consisting of two or more molecules held together by weak forces of attraction as opposed to chemical bonds. A simple example of a supramolecular system is a host-guest inclusion complex, in which a guest molecule becomes included within the cavity of a larger, cage-like organic host molecule (like a ball in a bucket). The most common family of host molecules are the cyclodextrins (CDs), cyclic forms of glucose sugar that take on a bucket-like shape in water, and strongly bind guest molecules inside their internal cavities. Building upon the previous success in my research group involving fluorescence-based investigations of the fundamental properties of host-guest inclusion systems, the transformative research to be supported by this proposal involves the novel application of such supramolecular systems in two important areas: 1)

超分子化学，或“超越分子的化学”，涉及由两个或多个分子通过弱吸引力而不是化学键结合在一起组成的结构。超分子体系的一个简单例子是主客体包合复合物，其中客体分子被包含在更大的笼状有机主体分子的空腔内（就像桶中的球）。最常见的宿主分子家族是环糊精（CD），葡萄糖的环状形式，在水中呈桶状，并在其内部空腔内强烈结合客体分子。在我的研究小组先前成功地对主客体包合体系的基本性质进行了基于荧光的研究的基础上，本提案所支持的变革性研究涉及这种超分子体系在两个重要领域的新应用：